Oncology & Cancer

Gene loss enhances metastasis and cancer progression

Investigators have discovered that the loss of the gene SLIT2 in circulating tumor cells regulates metastasis of prostate cancer tumors, according to a Northwestern Medicine study published in Science Advances.

Oncology & Cancer

Study illuminates precancerous 'clonal outgrowth' in blood cells

A common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may promote these diseases by altering the stem cells' programming of gene activity and ...

Oncology & Cancer

Possible new cancer treatment target discovered

Researchers at the University of Gothenburg have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice. This discovery may potentially enable future development of new drugs against ...

Genetics

Scientists identify genetic risk factors for opioid use disorder

A new human genomics study led by Yale scientists has identified genetic risk factors for opioid use disorder (OUD) and related substance use disorders according to a new large-scale genome-wide association study—increasing ...

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