Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the "holy grails" for cardiovascular scientists. The ability to repair heart muscle—especially by using a person's own cells—would ...
Nov 30, 2018
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By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...
Dec 24, 2020
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A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer. These findings, ...
Oct 4, 2019
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Systemic lupus erythematosus (SLE) is an autoimmune disease that affects all the organ systems of the body. This chronic disease includes periods of illness, called flare ups, and periods of remission, when symptoms are few. ...
Jul 11, 2022
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In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.
Sep 4, 2011
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In a new review of imaging studies spanning more than ten years, scientists find that a method of positron emission tomography (PET) safely and accurately detects dementia, including the most common and devastating form among ...
Jan 6, 2012
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How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has ...
Jun 10, 2022
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In a groundbreaking study, researchers from Brigham and Women's Hospital (BWH) have identified a related family of molecules believed to be a major root cause of pulmonary hypertension, a deadly vascular disease with undefined ...
Jun 24, 2014
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One person in Australia develops diabetes every five minutes, with up to half suffering peripheral nerve damage, meaning the slightest touch on the skin can cause pain. Now an international research team, led by Australian ...
Dec 12, 2016
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Leigh syndrome is the most severe mitochondrial disease in children. It causes severe muscle weakness, movement defects, and intellectual disabilities. It usually leads to death within the first years of life. No causative ...
Mar 26, 2021
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