Protein may represent a switch to turn off B cell lymphoma
Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...
Cancer
May 07, 2012 |
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Lymphoma therapy could deliver a double punch
B cell lymphomas are a group of cancers of that originate in lymphoid tissue from B cells, the specialized immune cell type that produces antibodies. The development of B cell lymphoma is associated with several known genetic ...
Cancer
Apr 30, 2012 |
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'Housekeeping' mechanism for brain stem cells discovered
Researchers at Columbia University Medical Center (CUMC) have identified a molecular pathway that controls the retention and release of the brain's stem cells. The discovery offers new insights into normal and abnormal neurologic ...
Neuroscience
Apr 22, 2012 |
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Exploring the antidepressant effects of testosterone
Testosterone, the primary male sex hormone, appears to have antidepressant properties, but the exact mechanisms underlying its effects have remained unclear. Nicole Carrier and Mohamed Kabbaj, scientists at Florida State ...
Psychology & Psychiatry
Apr 02, 2012 |
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Two targeted therapies act against Ewing's sarcoma tumors
A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson ...
Cancer
Apr 01, 2012 |
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Researchers validate the potential of a protein for the treatment of type 2 diabetes
Researchers at the Institute for Research in Biomedicine (IRB Barcelona, Spain)) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause ...
Diabetes
Mar 23, 2012 |
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Scientists link two cancer-promoting pathways in esophageal cancer
Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs ...
Cancer
Mar 19, 2012 |
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Study shows how the breakup of two proteins interferes with the immune system
Autoimmune diseases, such as Type I diabetes and rheumatoid arthritis, are caused by an immune system gone haywire, where the body's defense system assaults and destroys healthy tissues. A mutant form of a ...
Immunology
Mar 18, 2012 |
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BIM gene variation in East Asians found to explain resistance to cancer drugs
A multi-national research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.
Cancer
Mar 18, 2012 |
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Tobacco smoke affects early human embryonic development
(Medical Xpress) -- Scientists have gained insight into how second-hand tobacco smoke damages the earliest stages of human embryonic development.
Medical research
Mar 16, 2012 |
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Study shows how high-fat diets increase colon cancer risk
Epidemiologists have long warned that, in addition to causing obesity, eating too much fat and sugar puts a person at greater risk for colon cancer. Now, researchers at Temple University have established a link that may explain ...
Cancer
Mar 07, 2012 |
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New universal platform for cancer immunotherapy developed
(Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T c ...
Cancer
Mar 05, 2012 |
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Cocaine and the teen brain: Study offers insights into addiction
When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, Yale and other scientists have found. Now two new studies by a Yale team identify key genes ...
Neuroscience
Feb 21, 2012 |
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How mitochondrial DNA defects cause inherited deafness
(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed ...
Medical research
Feb 17, 2012 |
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Neurobiologists identify animal model for a deadly human metabolic disorder
In medical research, finding a reliable and cost-effective animal model can greatly enhance success in identifying disease mechanisms and genetic pathways, potentially cutting years off drug testing regimes and development ...
Neuroscience
Feb 13, 2012 |
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