Team identifies key protein causing excess liver production of glucose in diabetes
Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's ...
Medical research
Sep 28, 2011 |
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Common cholesterol drug safe, may improve learning disabilities in patients with neurofibromatosis
Researchers at Children's National Medical Center have found that a cholesterol-lowering statin drug appears to be safe in children with neurofibromatosis type 1 (NF1) and may improve learning disabilities, including verbal ...
Neuroscience
Sep 27, 2011 |
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Researchers identify pathways leading to activation of good fat
Researchers at the Joslin Diabetes Center have identified for the first time two molecular pathways that are critical to activating a type of "good" fat found in the body, a discovery that could play an important ...
Medical research
Sep 21, 2011 |
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Researchers find possible key to preventing chemotherapy resistance in ovarian cancer
For patients with ovarian cancer and their physicians, resistance to chemotherapy is a serious concern. However, researchers at Moffitt Cancer Center have identified a molecular pathway that may play a key role in the evolution ...
Cancer
Sep 15, 2011 |
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Scientists discover switch that turns white fat brown
Scientists have discovered a biological switch that gives energy-storing white fat the characteristics of energy-burning brown fat. The findings could lead to new strategies for treating obesity.
Medical research
Sep 06, 2011 |
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Low-dose naltrexone (LDN): Tricking the body to heal itself
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) ...
Medical research
Sep 02, 2011 |
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Research gives new hope to those with rare vascular cancer
A specific genetic alteration has been discovered as a defining feature of epithelioid hemangioendothelioma (EHE), a rare but devastating vascular cancer. These findings have also been used to develop a new diagnostic test ...
Cancer
Aug 31, 2011 |
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New compound may accelerate bone healing, prevent osteoporosis
An Indiana University scientist studying human bone growth has received a $2.6 million grant from the U.S. Department of Defense to study a chemical compound with potential to fight osteoporosis and accelerate broken bone ...
Medical research
Aug 17, 2011 |
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Breast cancer tumor suppressor gene silenced by low O2
Low oxygen can silence the BRCA1 tumor suppressor gene and contribute to the progression of cancer, according to a paper in the August 2011 issue of the journal Molecular and Cellular Biology. Silencing this particular gene i ...
Cancer
Aug 16, 2011 |
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Researchers identify a signaling pathway as possible target for cancer treatment
In a new study published in the August 16th issue of Developmental Cell, researchers at NYU Langone Medical Center identified a molecular mechanism that guarantees that new blood vessels form in the right place and with t ...
Medical research
Aug 15, 2011 |
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Researchers find molecular pathway that leads to inflammation in asthma
Researchers at the University of Pittsburgh School of Medicine have identified a molecular pathway that helps explain how an enzyme elevated in asthma patients can lead to increased mucus production and inflammation that ...
Diseases, Conditions, Syndromes
Aug 08, 2011 |
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Genetic link to Barrett's esophagus, esophageal cancer discovered
Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux ...
Genetics
Jul 26, 2011 |
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Specialized regulatory T cell stifles antibody production centers
A regulatory T cell that expresses three specific genes shuts down the mass production of antibodies launched by the immune system to attack invaders, a team led by scientists at The University of Texas MD Anderson Cancer ...
Medical research
Jul 25, 2011 |
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Cancer drugs may help treatment of schizophrenia
Researchers have revealed the molecular pathway that is affected during the onset of schizophrenia and successfully alleviated symptoms of the illness in mice, using a commonly used cancer drug.
Neuroscience
Jul 20, 2011 |
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Researchers develop compound to block signaling of cancer-causing protein
Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the ...
Cancer
Jul 17, 2011 |
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