News tagged with molecular pharmacology
Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...
Cancer
May 13, 2013 |
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Brain region may hold key to aging
While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein ...
Neuroscience
May 01, 2013 |
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Researchers identify and block protein that interferes with appetite-suppressing hormone
Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite ...
Medical research
Apr 17, 2013 |
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New monoclonal antibody developed that can target proteins inside cancer cells
Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer ...
Cancer
Mar 13, 2013 |
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Researchers reveal mechanism to halt cancer cell growth, discover potential therapy
University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.
Cancer
Feb 04, 2013 |
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Scientists find gene interactions that make cocaine abuse death eight times more likely
Scientists have identified genetic circumstances under which common mutations on two genes interact in the presence of cocaine to produce a nearly eight-fold increased risk of death as a result of abusing the drug.
Genetics
Jan 22, 2013 |
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Preventing prostate cancer through androgen deprivation may have harmful effects
Mice deficient in PTEN in the prostate developed stable precancers. Androgen deprivation promoted progression to invasive prostate cancer. Patients with PTEN-deficient prostate precancers may not benefit from androgen deprivation ...
Cancer
Dec 20, 2012 |
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Scientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography ...
Cancer
Dec 10, 2012 |
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Researchers discover adverse effects of Bisphenol A on calcium channels
(Medical Xpress)—Bisphenol A, a substance found in many synthetic products, is considered to be harmful, particularly, for fetuses and babies. Researchers from the University of Bonn have now shown in experiments on cells ...
Medical research
Dec 06, 2012 |
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New mechanism of action for PARP inhibitors discovered
New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led ...
Cancer
Nov 09, 2012 |
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New drug could treat Alzheimer's, multiple sclerosis and brain injury
A new class of drug developed at Northwestern University Feinberg School of Medicine shows early promise of being a one-size-fits-all therapy for Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic ...
Neuroscience
Jul 24, 2012 |
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Scientists solve 1,000 protein structures from infectious disease organisms
Investigators at the Center for Structural Genomics of Infectious Diseases (CSGID) and the Seattle Structural Genomics Center for Infectious Disease (SSGCID) announced today that they reached a significant milestone by determining ...
Diseases, Conditions, Syndromes
Jun 05, 2012 |
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Purdue researchers reveal role of protein mutation in Parkinson's disease
Purdue University researchers revealed how a mutation in a protein shuts down a protective function needed to prevent the death of neurons in Parkinson's disease, possibly opening the door to new drug strategies to treat ...
Parkinson's & Movement disorders
Feb 21, 2012 |
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US Patent Office affirms 'Zamore Design Rule' patents
The United States Patent and Trademark Office has reaffirmed the validity of four important patents in the field of RNA therapeutics.
Medical research
Dec 12, 2011 |
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New protocols improve detection of microRNAs for diagnosis
MicroRNAs (miRNAs) that regulate processes including fertilization, development, and aging show promise as biomarkers of disease. They can be collected from routinely collected fluids such as blood, saliva, and urine. However, ...
Medical research
Dec 07, 2011 |
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