Researchers identify mechanism that makes breast cancer invasive
A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer ...
Cancer
Mar 29, 2012 |
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Researchers identify new regulator in allergic diseases
Researchers have taken a critical step in understanding how allergic reactions occur after identifying a genetic signature for regulation of a key immune hormone, interleukin (IL-13).
Immunology
Mar 28, 2012 |
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Study identifies gene expression abnormalities in autism
A study led by Eric Courchesne, PhD, director of the Autism Center of Excellence at the University of California, San Diego School of Medicine has, for the first time, identified in young autism patients genetic ...
Autism spectrum disorders
Mar 22, 2012 |
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Aurora-A hinders tumor-suppressor to allow chemotherapy resistance
A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists ...
Cancer
Feb 27, 2012 |
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The leading cause of death for diabetics: Getting to the heart of problem
Millions of people suffer from type 2 diabetes. The leading cause of death in these patients is heart disease. Joseph Hill and colleagues, at the University of Texas Southwestern Medical Center, Dallas, have now identified, ...
Diseases, Conditions, Syndromes
Feb 13, 2012 |
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New therapeutic target to combat liver cancer discovered
Spanish researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the ...
Cancer
Jan 26, 2012 |
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Researchers map potential genetic origins, pathways of lung cancer in nonsmokers
Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers -- a first step in developing potential therapeutic ...
Cancer
Jan 09, 2012 |
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New research finds trigger for breast cancer spread
Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential ...
Cancer
Jan 03, 2012 |
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New potential therapeutic target identified for Diffuse Large B-Cell Lymphoma
Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma (DLBCL), the most aggressive and ...
Cancer
Nov 28, 2011 |
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Researchers discover Achilles' heel in lethal form of prostate cancer
An international team of researchers led by clinicians at Weill Cornell Medical College have discovered a genetic Achilles' heel in an aggressive type of prostate cancer -- a vulnerability they say can be attacked by a targeted ...
Cancer
Nov 17, 2011 |
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Panel of melanoma mutations opens door to new treatment possibilities
Researchers have developed a new genetic screening tool that will aid in the investigation of possible treatments for patients with melanoma and the unique genetic mutations that may accompany the disease, according to data ...
Cancer
Nov 15, 2011 |
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Glioblastoma multiforme in the Dock
Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. ...
Cancer
Nov 14, 2011 |
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Antifolates show promise against NSCLC subtype
Patients with non-small cell lung cancer who have mutations in the KRAS gene should respond well to the antifolate class of drugs, according to results of a recent study conducted by Quintiles comparing human lung cancer ...
Cancer
Nov 14, 2011 |
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New approaches may prevent certain side effects in BRAF mutation-positive melanoma
Findings from preclinical studies in a skin cancer model showed that next-generation BRAF inhibitors used alone, or first-generation BRAF inhibitors used in combination with an epidermal growth factor receptor inhibitor, ...
Cancer
Nov 13, 2011 |
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Researchers develop more effective way to discover and test potential cancer drugs
Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors.
Cancer
Nov 13, 2011 |
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