News tagged with monoclonal antibodies

Monoclonal antibody targets, kills leukemia cells

Researchers at the University of California, San Diego Moores Cancer Center have identified a humanized monoclonal antibody that targets and directly kills chronic lymphocytic leukemia (CLL) cells.

Cancer created Mar 25, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers develop novel anti-body vaccine that blocks addictive nicotine chemicals from reaching the brain

Researchers at Weill Cornell Medical College have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction.

Medical research created Jun 27, 2012 | popularity 5 / 5 (7) | comments 7 | with audio podcast

Palivizumab cuts number of days of wheezing in preemies

(HealthDay)—Many pre-term babies suffer recurrent episodes of wheezing. Now, researchers say a common infection is a likely culprit and they may be able to prevent the breathing problems.

Diseases, Conditions, Syndromes created May 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study offers clues to making vaccine for infant respiratory illness

An atomic-level snapshot of a respiratory syncytial virus (RSV) protein bound to a human antibody represents a leap toward developing a vaccine for a common—and sometimes very serious—childhood disease. ...

Diseases, Conditions, Syndromes created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

Cancer created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New monoclonal antibody developed that can target proteins inside cancer cells

Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer ...

Cancer created Mar 13, 2013 | popularity 5 / 5 (6) | comments 0 | with audio podcast

First human tests of meth medication completed

(Medical Xpress)—InterveXion Therapeutics LLC and the University of Arkansas for Medical Sciences (UAMS) have successfully completed dosing in the first human safety study of a medication to help methamphetamine users fight ...

Medications created Dec 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

New drug may help those who can't take statins

(HealthDay)—An experimental drug may help patients who can't tolerate statins lower their cholesterol, a new Australian study suggests.

Cardiology created Nov 05, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Scientists identify new target for lung cancer treatment

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...

Cancer created Nov 01, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Ebola antibody treatment, produced in plants, protects monkeys from lethal disease

A new Ebola virus study resulting from a widespread scientific collaboration has shown promising preliminary results, preventing disease in infected nonhuman primates using monoclonal antibodies.

Medical research created Oct 15, 2012 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Monoclonal antibody effective therapy for diabetic retinopathy

(HealthDay)—An antibody can reduce retinal vascular leakage and inflammation in rat models of diabetic retinopathy, according to a study published online Oct. 1 in Diabetes.

Diabetes created Oct 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Antibody prevents hepatitis C in animal model

A monoclonal antibody developed by MassBiologics of the University of Massachusetts Medical School (UMMS) and tested in an animal model at the Texas Biomedical Research Institute, prevents infection by the hepatitis C virus ...

Diseases, Conditions, Syndromes created Aug 30, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Dual action polyclonal antibody may offer more effective, safer protection against osteoporosis

A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments.

Medical research created Aug 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find potential key to new treatment for mantle cell lymphoma

Researchers at Moffitt Cancer Center and colleagues have demonstrated that the inhibition of signal transducer and activator of transcription 3 (STAT3) in mouse models of mantle cell lymphoma (MCL), an aggressive and incurable ...

Cancer created Jul 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Mayo Clinic uses new approach to reverse multiple sclerosis in mice models

Mayo Clinic researchers have successfully used smaller, folded DNA molecules to stimulate regeneration and repair of nerve coatings in mice that mimic multiple sclerosis (MS). They say the finding, published today in the ...

Medical research created Jun 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

Monoclonal antibodies

Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the generic drug name ends in -mab (see "Nomenclature of monoclonal antibodies").

For more information about Monoclonal antibodies, read the full article at Wikipedia.
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