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Monocyte

Monocytes are a type of white blood cell and are part of the innate immune system of vertebrates including all mammals (including humans), birds, reptiles, and fish. Monocytes play multiple roles in immune function. Such roles include: (1) replenish resident macrophages and dendritic cells under normal states, and (2) in response to inflammation signals, monocytes can move quickly (approx. 8-12 hours) to sites of infection in the tissues and divide/differentiate into macrophages and dendritic cells to elicit an immune response. Half of them are stored in the spleen. Monocytes are usually identified in stained smears by their large kidney shaped or notched nucleus.

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Vitamin D may prevent clogged arteries in diabetics

People with diabetes often develop clogged arteries that cause heart disease, and new research at Washington University School of Medicine in St. Louis suggests that low vitamin D levels are to blame.

Diabetes created Nov 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Bone marrow holds secrets for treating colitis and Crohn's

(Medical Xpress)—Michigan State University researchers have unlocked secrets in bone marrow that could lead to improved treatments for colitis and Crohn's disease.

Medical research created Sep 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Early activation of immune response could lead to better vaccines

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a new "first response" mechanism that the immune system uses to respond to infection. The findings challenge the current understanding ...

Immunology created Aug 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Microneedle vaccine patch boosts flu protection through robust skin cell immune response

Recent research found that microneedle vaccine patches are more effective at delivering protection against influenza virus in mice than subcutaneous or intramuscular inoculation. A new, detailed analysis of the early immune ...

Immunology created Mar 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New light shed on cause of lung injury in severe flu

While some scientists report engineering a super virulent strain of the H5N1 influenza virus, which could potentially wipe out a significant percentage of the human population, another group of researchers from the United ...

Diseases, Conditions, Syndromes created Feb 29, 2012 | popularity not rated yet | comments 0

Study shows promising multiple sclerosis treatment targets immune cells to increase neuroprotection

Laquinimod is an orally available synthetic compound that has been successfully evaluated in phase II/III clinical studies for the treatment of relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of laquinimod ...

Medical research created Dec 06, 2011 | popularity not rated yet | comments 0

Alcohol impairs the body's ability to fight off viral infection

Alcohol is known to worsen the effects of disease, resulting in longer recovery period after trauma, injury or burns. It is also known to impair the anti-viral immune response, especially in the liver, including response ...

Health created Sep 30, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study identifies novel role for a protein that could lead to new treatments for rheumatoid arthritis

A new study by rheumatologists at Hospital for Special Surgery in New York has shown that a powerful pro-inflammatory protein, tumor necrosis factor (TNF), can also suppress aspects of inflammation. The researchers say the ...

Medical research created May 22, 2011 | popularity not rated yet | comments 0 | with audio podcast

Serendipity leads to lifesaving discovery

McGill research team recently published new findings in the New England Journal of Medicine, pointing to a critical role for IRF8 in the development and function of monocytes and dendritic cells and in protecting against ...

Medical research created May 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

Men's and women's immune systems respond differently to PTSD

Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA ...

Psychology & Psychiatry created Apr 26, 2011 | popularity not rated yet | comments 0 | with audio podcast