Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body's wound healing response to various forms of damage. When accompanied ...
Jul 11, 2022
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Determining how SARS-CoV-2, the virus causing COVID-19, moves from an early stage of infection, when patients are largely asymptomatic, into a later stage in which people may experience life-threatening inflammation in the ...
Jun 14, 2022
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A multidisciplinary team of Northwestern Medicine investigators has discovered striking differences in gene expression of monocytes—specialized immune cells—in the developing fetus, according to findings published in ...
Jun 10, 2022
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A study led by researchers at Boston Children's Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the ...
Apr 6, 2022
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New lung research from an international team of scientists could offer doctors a new way to detect and monitor progressive lung diseases—and may also shed light on the fundamental causes of those conditions.
Feb 1, 2022
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Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows ...
Jan 18, 2022
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In the decade since the advent of CRISPR-Cas9 gene editing, researchers have used the technology to delete or change genes in a growing number of cell types. Now, researchers at Gladstone Institutes and UC San Francisco (UCSF) ...
May 11, 2021
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Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University (TMDU) describe an ingenious strategy against chronic myelomonocytic ...
Apr 16, 2021
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The cause of the inflammatory lung disease sarcoidosis is unknown. In a new study, researchers at Karolinska Institutet have investigated whether a type of immune cell called a monocyte could be a key player in sarcoidosis ...
Jan 21, 2021
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Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. ...
Jan 13, 2021
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