Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron, a discovery that will enable scientists to study how this process goes awry in disease, according to a study ...
Apr 8, 2024
0
29
A mutated protein expressed in lysosomes may contribute to Parkinson's disease, according to a new Northwestern Medicine study published in the Journal of Cell Biology.
Mar 12, 2024
0
17
Researchers at Nagoya University in Japan have discovered a relationship between the progression of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the disruption of mitochondria-associated membranes ...
Jan 17, 2024
0
119
Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by motor neuron disease (MND), also known as amyotrophic lateral ...
Jul 21, 2023
0
98
My name is Antonio and I suffer from spinal muscular atrophy (SMA, for friends). My life expectancy was only a few years when I was born, almost half a century ago. And all because I "got" a rare, neurodegenerative disease, ...
Jun 15, 2023
1
5
Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.
Mar 22, 2023
0
1443
In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus ...
Mar 16, 2023
0
80
University of Malta researchers have discovered a potential new drug target for amyotrophic lateral sclerosis (ALS), according to a new study published in the Neurobiology of Aging journal.
Mar 14, 2023
0
3
A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...
Mar 13, 2023
0
575
A research team led by Professor Haruhisa Inoue of CiRA and Professor Hiroshi Nagashima of Meiji University has created a new porcine ALS model by introducing the human superoxide dismutase 1 (SOD1) gene with a mutation associated ...
Jan 13, 2023
0
2
