Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University ...
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(Medical Xpress)—Queensland scientists will begin clinical trials of treatment for spinal cord injuries after discovering dramatic improvements in balance and coordination when blocking a protein.
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Imagine if you could open up your brain and look inside. What you would see is a network of nerve cells called neurons, each with its own internal highway system for transporting essential materials between ...
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Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known ...
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Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic ...
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The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis (ALS) – blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease – may ...
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Biologists from the Ruhr-Universität Bochum have explored how to protect neurons that control movements from dying off. In the journal Molecular and Cellular Neuroscience they report that the molecule 7,8-Dihydroxyflavone, also k ...
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New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
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A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman ...
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When motors break down, getting where you want to go becomes a struggle. Problems arise in much the same way for critical brain receptors when the molecular motors they depend on fail to operate. Now, researchers reporting ...
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Research has shown that mutations in the psen1 gene are common in the familial forms of Alzheimer's disease, and the Presenilin-1 protein that the gene encodes is known to be involved in the cleavage of the amyloid precursor ...
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(Medical Xpress)—A Motor Neurone Disease (MND) Association funded research project at UCL has given new insights into the structure and function of an MND gene called C9ORF72. The work is published in the journal Scientific Re ...
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Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases—amyotrophic lateral sclerosis (ALS), and frontotemporal ...
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Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
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(Medical Xpress)—The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.
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