An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone ...
May 17, 2018
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Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.
Apr 20, 2018
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Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have characterized the mechanism that initiates the pathological aggregation of the protein FUS, which plays a central role in two distinct neurodegenerative diseases.
Apr 20, 2018
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A major step forward has been made by researchers at the University of St Andrews towards finding new treatments for Spinal Muscular Atrophy (SMA), the commonest genetic cause of infant death.
Apr 18, 2018
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About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There ...
Mar 8, 2018
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University of Bath scientists have developed a better understanding of a key protein associated with brain diseases including ALS (motor neurone disease) and dementia by studying how it enters central nervous system cells.
Feb 28, 2018
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The split personality of a nerve cell illustrates a puzzle. Nerve cells are divided in two domains – the axon sends signals and the dendrites receive them. Axonal and dendritic proteins embedded in the membrane at either ...
Feb 22, 2018
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ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new USC Stem Cell study published in Nature Medicine.
Feb 5, 2018
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Respiratory infections peak during the winter months, and most people recover within a few weeks. But for those with a rare genetic lung disease, the sniffling, coughing and congestion never end. The tiny hairlike structures ...
Jan 24, 2018
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University of California, Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig's disease, in mice, extending their ...
Dec 20, 2017
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