Researchers find new target for Alzheimer's drug development
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia
Dec 03, 2012 |
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Study explains why some teenagers more prone to binge drinking
New research helps explain why some teenagers are more prone to drinking alcohol than others. The study, led by King's College London's Institute of Psychiatry (IoP) and published in Proceedings of the National Academy of ...
Genetics
Dec 03, 2012 |
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Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
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Studies in mice confirm that mutations in the gene, UBE3B, cause a rare genetic disorder in children
Researchers have defined the gene responsible for a rare developmental disorder in children. The team showed that rare variation in a gene involved in brain development causes the disorder. This is the first time that this ...
Genetics
Nov 29, 2012 |
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Next-generation treatments for Fragile X syndrome
A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Ita ...
Psychology & Psychiatry
Nov 29, 2012 |
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Study solves birth and migration mysteries of cortex's powerful inhibitors, 'chandelier' cells
A team at CSHL for the 1st time reveals the birth timing and embryonic origin of a critical class of inhibitory brain cells called chandelier cells, tracing the specific paths they take during early development into the cerebral ...
Neuroscience
Nov 22, 2012 |
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Discovery of molecular pathway of Alzheimer's disease reveals new drug targets
The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study ...
Alzheimer's disease & dementia
Nov 20, 2012 |
4.5 / 5 (2) |
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Study identifies a potential cause of Parkinson's disease
Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...
Parkinson's & Movement disorders
Nov 19, 2012 |
4.3 / 5 (6) |
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Faulty development of immature brain cells causes hydrocephalus
Researchers at the University of Iowa have discovered a new cause of hydrocephalus, a devastating neurological disorder that affects between one and three of every 1,000 babies born. Working in mice, the researchers identified ...
Medical research
Nov 19, 2012 |
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For brain tumors, origins matter
(Medical Xpress)—Since stem cells and progenitor cells are regulated by different growth factors, brain tumors arising from these cells might respond differently to different therapies. Researchers at Sanford-Burnham ...
Cancer
Nov 13, 2012 |
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Two heads are better than one: Gene expression reveals molecular mechanisms underlying evolution of cerebral cortex
Dramatic expansion of the human cerebral cortex, over the course of evolution, accommodated new areas for specialized cognitive function, including language. Understanding the genetic mechanisms underlying ...
Neuroscience
Nov 09, 2012 |
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Study finds diabetes raises levels of proteins linked to Alzheimer's features
Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. ...
Alzheimer's disease & dementia
Oct 26, 2012 |
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Challenging Parkinson's dogma
Scientists may have discovered why the standard treatment for Parkinson's disease is often effective for only a limited period of time. Their research could lead to a better understanding of many brain disorders, from drug ...
Medical research
Oct 24, 2012 |
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Scientists aim to analyse a whole mouse brain under the electron microscope
What happens in the brain when we see, hear, think and remember? To be able to answer questions like this, neuroscientists need information about how the millions of neurons in the brain are connected to ...
Neuroscience
Oct 23, 2012 |
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Immune cells of the blood might replace dysfunctional brain cells
Blood-circulating immune cells can take over the essential immune surveillance of the brain, this is shown by scientists of the German Center for Neurodegenerative Diseases and the Hertie Institute for Clinical Brain Research ...
Medical research
Oct 22, 2012 |
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