For decades, the enormous disease-curing potential of human stem cells has been thwarted by the inability to produce sufficient quantities of mature human cells in vivo—in a living organism.
May 13, 2020
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130
Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.
Feb 11, 2013
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Daughters inherit two X chromosomes (one from the mother and one from the father), while sons inherent an X chromosome only from the mother. In new research published in Molecular Cell, investigators at Massachusetts General ...
Mar 11, 2024
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23
A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at ...
Jul 24, 2023
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57
When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are silent. Somehow, at an early stage of development, embryo genes must be switched on. Without this vital 'genes on' switch in the embryo, none ...
Feb 1, 2023
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48
Cellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers revealed the secrets underlying cell competition and what features can pre-determine ...
Jul 20, 2021
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Wei Yan, MD, Ph.D., and his research group have solved a longstanding mystery and scientific debate about the mechanism underlying the gamete and embryo transport within the fallopian tube. Using a mouse model that lacked ...
May 24, 2021
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11
A UCLA-led study reveals a new role for a gene that's associated with autism spectrum disorder, intellectual disability and language impairment.
Feb 12, 2020
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321
RIKEN researchers have determined how a protein that transports essential amino acids across the placenta contributes to normal embryonic development in mammals.
Dec 27, 2019
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342
Though epigenetic disorders—diseases caused by faulty gene expression—are still rare overall, babies born using fertility treatments have up to an 11-fold higher risk of inheriting them. According to a new mouse study ...
Nov 26, 2019
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