News tagged with mouse embryo


Genes for autism and schizophrenia only active in developing brains

Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.

Genetics created Feb 11, 2013 | popularity 3.4 / 5 (30) | comments 0 | with audio podcast

Mutation in gene that's critical for human development linked to arrhythmia

Arrhythmia is a potentially life-threatening problem with the rate or rhythm of the heartbeat, causing it to go too fast, too slow or to beat irregularly. Arrhythmia affects millions of people worldwide.

Genetics created Dec 27, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New research refutes claim iPSCs are prone to immune response

(Medical Xpress)—Researchers in Japan have injected induced pluripotent stem cells (iPSCs) from mice back into genetically identical mice and report that doing so caused no immune reaction. This contradicts the results ...

Medical research created Jan 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Gene knockout stops immune cell development

(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute have identified the key gene in ensuring that our immune defences develop infection-fighting cells. No cells of the adaptive immune system ...

Immunology created Dec 11, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Inheritance of mitochondrial disease determined when mother is still an embryo

(Medical Xpress)—The risk of a child to inherit mitochondrial diseases - i. e. malfunction in what is usually referred to as the power plants of the cell - is largely decided when the future mother herself is still an embryo. ...

Genetics created Oct 08, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Research identifies protein that regulates key 'fate' decision in cortical progenitor cells

Researchers at Cold Spring Harbor Laboratory (CSHL) have solved an important piece of one of neuroscience's outstanding puzzles: how progenitor cells in the developing mammalian brain reproduce themselves while also giving ...

Neuroscience created Sep 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study implicates marijuana use in pregnancy problems

New research indicates marijuana-like compounds called endocannabinoids alter genes and biological signals critical to the formation of a normal placenta during pregnancy and may contribute to pregnancy complications like ...

Medical research created Sep 12, 2012 | popularity not rated yet | comments 1 | with audio podcast

Artificial thymus tissue enables maturation of immune cells

The thymus plays a key role in the body's immune response. It is here where the T lymphocytes or T cells, a major type of immune defence cells, mature. Different types of T cells, designated to perform specific ...

Immunology created Mar 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists discover primitive gut's role in left-right patterning

Scientists have found that the gut endoderm has a significant role in propagating the information that determines whether organs develop in the stereotypical left-right pattern. Their findings are published 6 March 2012 in ...

Medical research created Mar 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Artificial 'womb' unlocks secrets of early embryo development

(Medical Xpress) -- Pioneering work by a leading University of Nottingham scientist has helped reveal for the first time a vital process in the development of the early mammalian embryo.

Medical research created Mar 02, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Scientists identify crucial cell and signaling pathway in placental blood stem cell niche

(Medical Xpress) -- UCLA stem-cell researchers have identified a certain type of cell and a signaling pathway in the placental niche that play a key role in stopping blood stem cells from differentiating into mature blood ...

Medical research created Mar 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists use an old theory to discover new targets in the fight against breast cancer

Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have ...

Cancer created Feb 07, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

SUMO-snipping protein plays crucial role in T and B cell development

When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...

Genetics created Jan 27, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Cleft lip corrected genetically in mouse model

Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way ...

Genetics created Nov 28, 2011 | popularity not rated yet | comments 0 | with audio podcast

Maternal diabetes impairs methylation of imprinted gene in oocytes

For the first time, researchers have shown that poorly controlled maternal diabetes has an adverse effect on methylation of the maternal imprinting gene Peg3, contributing to impaired development in offspring.

Diabetes created Mar 20, 2013 | popularity 5 / 5 (1) | comments 0