News tagged with mouse model

Related topics: stem cells , cancer cells , cells , immune cells , animal model




Research illuminates molecular mechanism for why stimulating environment may protect against Alzheimer's disease

"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease. Previous studies have shown that keeping the mind active, exercising and social interactions may ...

Alzheimer's disease & dementia created Mar 06, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Age-related dementia may begin with neurons' inability to dispose of unwanted proteins

A team of European scientists from the University Medical Center Hamburg-Eppendorf (UKE) and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne in ...

Alzheimer's disease & dementia created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0

Scientists make mouse model of human cancer, demonstrate cure

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

Cancer created Mar 05, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers utilize genetically corrected stem cells to spark muscle regeneration

Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy ...

Medical research created Mar 05, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

A nanogel-based treatment for lupus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, ...

Diseases, Conditions, Syndromes created Mar 01, 2013 | popularity not rated yet | comments 0

A coordinated response to cardiac stress

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain ...

Cardiology created Mar 01, 2013 | popularity not rated yet | comments 0

Study identifies growth factor essential to the most common malignant pediatric brain tumor

A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...

Cancer created Feb 28, 2013 | popularity not rated yet | comments 0 | with audio podcast

Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms ...

Diseases, Conditions, Syndromes created Feb 22, 2013 | popularity 5 / 5 (1) | comments 0

Variations within influenza strain may explain varying patient response

(Medical Xpress)—Just the mention of H1N1 can conjure up images of long lines of people waiting to be vaccinated, news reports of the severity of the pandemic and the count of the number of people who perished from the ...

Diseases, Conditions, Syndromes created Feb 19, 2013 | popularity not rated yet | comments 0

Novel herbal compound offers potential to prevent and treat Alzheimer's disease

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, ...

Alzheimer's disease & dementia created Feb 16, 2013 | popularity 5 / 5 (5) | comments 0

Deep genomic analysis identifies a micro RNA opponent for ovarian cancer

Researchers employed an extensive analysis of genomic information to identify a new, high-risk cohort of ovarian cancer patients, characterize their tumors, find a potential treatment and test it in mouse models of the disease.

Cancer created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0

Mouse models fail to reproduce inflammatory genomic response to serious injuries

Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.

Inflammatory disorders created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Mouse model improves understanding of clear cell sarcoma

Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue ...

Cancer created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study suggests improved treatment alternative for lymphoid leukemia

Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models.

Cancer created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists discover promising target to block Staphylococcus infection

National Institutes of Health (NIH) scientists have identified a promising lead for developing a new type of drug to treat infection caused by Staphylococcus aureus, a bacterium that frequently resists traditional antibi ...

Diseases, Conditions, Syndromes created Feb 10, 2013 | popularity 5 / 5 (4) | comments 1 | with audio podcast