News tagged with mouse model
Related topics: stem cells , cancer cells , cells , immune cells , animal model
Staphylococcus aureus: Why it just gets up your nose
A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. au ...
Diseases, Conditions, Syndromes
Dec 27, 2012 |
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Scientists home in on cause of osteoarthritis pain
Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could ...
Arthritis & Rheumatism
Dec 27, 2012 |
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Many causes for learning lags in tumor disorder
(Medical Xpress)—The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine ...
Neuroscience
Dec 21, 2012 |
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Scientists uncover cells at the origin of basal cell carcinoma
For years researchers have been trying to identify the molecular changes that occur in tumour-initiating cells from the very first oncogenic mutation to the development of invasive tumors. The most frequently ...
Cancer
Dec 21, 2012 |
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Two novel treatments for retinitis pigmentosa move closer to clinical trials
Two recent experimental treatments—one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy—have been shown to produce long-term improvement in visual function in mouse models of retinitis ...
Ophthalmology
Dec 20, 2012 |
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Transplanted neural stem cells treat ALS in mouse model
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is untreatable and fatal. Nerve cells in the spinal cord die, eventually taking away a person's ability to move or even breathe. A ...
Medical research
Dec 19, 2012 |
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Study offers insights into role of muscle weakness in Down syndrome
It is well known that people with Down syndrome (DS) suffer from marked muscle weakness. Even the simple tasks of independent living, such as getting out of a chair or climbing a flight of stairs, can become major obstacles. ...
Psychology & Psychiatry
Dec 17, 2012 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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Researchers discover new molecule linked to late-stage breast cancer
Researchers at Case Western Reserve University School of Medicine have identified a molecule linked to more aggressive forms of breast cancer – a discovery that could point the way to potential cures.
Cancer
Dec 17, 2012 |
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Study unmasks regulator of healthy life span
A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and ...
Medical research
Dec 17, 2012 |
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Harnessing the ID in glioma
Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Cancer
Dec 17, 2012 |
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Hard-to-treat Myc-driven cancers may be susceptible to drug already used in clinic
Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers ...
Cancer
Dec 14, 2012 |
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Uncovering a flaw in drug testing for chronic anxiety disorder
Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...
Medical research
Dec 13, 2012 |
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Team inhibits Alzheimer's biomarkers in animal model by targeting astrocytes
A research team composed of University of Kentucky researchers has published a paper which provides the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease. The UK Sanders-Brown ...
Alzheimer's disease & dementia
Dec 11, 2012 |
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Scientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography ...
Cancer
Dec 10, 2012 |
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