News tagged with mouse model
Related topics: stem cells , cancer cells , cells , immune cells , animal model
Harnessing the ID in glioma
Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Cancer
Dec 17, 2012 |
not rated yet |
0
Hard-to-treat Myc-driven cancers may be susceptible to drug already used in clinic
Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers ...
Cancer
Dec 14, 2012 |
not rated yet |
0
Uncovering a flaw in drug testing for chronic anxiety disorder
Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...
Medical research
Dec 13, 2012 |
5 / 5 (1) |
0
|
Team inhibits Alzheimer's biomarkers in animal model by targeting astrocytes
A research team composed of University of Kentucky researchers has published a paper which provides the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease. The UK Sanders-Brown ...
Alzheimer's disease & dementia
Dec 11, 2012 |
5 / 5 (2) |
0
Scientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography ...
Cancer
Dec 10, 2012 |
not rated yet |
0
Pre-clinical data shows Angiocidin effective against leukemia
Angiocidin, a novel tumor-inhibiting protein, has been shown to reduce acute myeloid leukemia (AML) cells in vivo by almost two-thirds in pre-clinical experiments.
Cancer
Dec 09, 2012 |
not rated yet |
0
Research suggests a new strategy to prevent or halt periodontal disease
Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In ...
Medical research
Dec 07, 2012 |
4.8 / 5 (6) |
0
|
Study shows antibody therapy clears Alzheimer's plaques in mice
Antibodies against amyloid beta (Aβ) protein deposits that are thought to play a role in Alzheimer's disease have shown some success in preventing the buildup of deposits in animals, but they have not been effective at removing ...
Alzheimer's disease & dementia
Dec 05, 2012 |
5 / 5 (5) |
0
|
ALS TDI and Gladstone Institutes collaborate to discover potential ALS treatments
The ALS Therapy Development Institute (ALS TDI) and the Gladstone Institutes today announced the formation of a research collaboration to speed the discovery of potential treatments for ALS through the preclinical drug development ...
Medical research
Dec 04, 2012 |
not rated yet |
0
Researchers make breakthrough in arthritis research
Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.
Medical research
Dec 03, 2012 |
5 / 5 (1) |
0
|
Researchers find new target for Alzheimer's drug development
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia
Dec 03, 2012 |
5 / 5 (1) |
0
|
Study explains why some teenagers more prone to binge drinking
New research helps explain why some teenagers are more prone to drinking alcohol than others. The study, led by King's College London's Institute of Psychiatry (IoP) and published in Proceedings of the National Academy of ...
Genetics
Dec 03, 2012 |
4 / 5 (1) |
0
|
Biomarker progress offers hope for early autism spectrum disorder detection
Autism spectrum disorders (ASD) are neurodevelopmental disorders typically characterized by difficulties in social interactions and delayed or abnormal language development. Although ASD reportedly affects 1 in 88 people ...
Autism spectrum disorders
Nov 30, 2012 |
2 / 5 (1) |
0
|
Molecular root of 'exhausted' T cells in chronic viral infection
When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system ...
Medical research
Nov 29, 2012 |
5 / 5 (2) |
0
|
Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
5 / 5 (1) |
0
|
