News tagged with mouse model
Related topics: stem cells , cancer cells , cells , immune cells , animal model
Study identifies a potential cause of Parkinson's disease
Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...
Parkinson's & Movement disorders
Nov 19, 2012 |
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Faulty development of immature brain cells causes hydrocephalus
Researchers at the University of Iowa have discovered a new cause of hydrocephalus, a devastating neurological disorder that affects between one and three of every 1,000 babies born. Working in mice, the researchers identified ...
Medical research
Nov 19, 2012 |
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Researchers report potential new treatment to stop Alzheimer's disease
Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons.
Alzheimer's disease & dementia
Nov 15, 2012 |
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Studies investigate oxygen's impact as a factor in transplantation
Two studies published in the current issue of Cell Transplantation (21:7), now freely available on-line, investigate the role of oxygen in cell transplantation.
Medical research
Nov 15, 2012 |
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Potential new technique for anticancer radiotherapy could provide alternative to brachytherapy
A promising new approach to treating solid tumors with radiation was highly efficacious and minimally toxic to healthy tissue in a mouse model of cancer, according to data published in Cancer Research, a journal of the Am ...
Cancer
Nov 15, 2012 |
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Stem cell finding could advance immunotherapy for lung cancer
A University of Cincinnati (UC) Cancer Institute lung cancer research team reports that lung cancer stem cells can be isolated—and then grown—in a preclinical model, offering a new avenue for investigating immunotherapy ...
Cancer
Nov 13, 2012 |
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For brain tumors, origins matter
(Medical Xpress)—Since stem cells and progenitor cells are regulated by different growth factors, brain tumors arising from these cells might respond differently to different therapies. Researchers at Sanford-Burnham ...
Cancer
Nov 13, 2012 |
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Study discovers a new live vaccine approach for SARS and novel coronaviruses
Rapid mutation has long been considered a key to viral adaptation to environmental change. But in the case of the coronavirus responsible for deadly severe acute respiratory syndrome (SARS), collaborating researchers at the ...
Medical research
Nov 12, 2012 |
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A new development in the relief of spasms related to amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an occurrence rate in France similar to multiple sclerosis (two to three new cases per year for every 100,000 residents). It has a specific affect on ...
Diseases, Conditions, Syndromes
Nov 06, 2012 |
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Scientists identify new target for lung cancer treatment
A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...
Cancer
Nov 01, 2012 |
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Mice with 'humanized' livers improve early drug testing
Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.
Medical research
Oct 31, 2012 |
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Drug shows promise in animal model of Alzheimer's and Parkinson's with dementia
New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline ...
Alzheimer's disease & dementia
Oct 26, 2012 |
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Study finds diabetes raises levels of proteins linked to Alzheimer's features
Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. ...
Alzheimer's disease & dementia
Oct 26, 2012 |
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Mouse model could help identify viral vectors that may cause tumors
Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect. The study appears in ...
Cancer
Oct 26, 2012 |
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Researchers develop new drug delivery system for bladder cancer using nanoparticles
A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, ...
Cancer
Oct 25, 2012 |
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