In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes—the effect on the finished dish can be quite different, depending ...
Apr 3, 2024
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Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage ...
Mar 8, 2023
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Scientists at Children's Hospital of Philadelphia (CHOP) have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators ...
Aug 2, 2021
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Microbial communities in the intestine—also known as the gut microbiome—are vital for human digestion, metabolism and resistance to colonization by pathogens. The gut microbiome composition in infants and toddlers changes ...
May 8, 2020
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Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect ...
Jun 11, 2019
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Roughly a third of all genes in the mammalian genome are essential for life. A new article in Nature, from an international, multi-institutional research team, including Baylor College of Medicine, describes the large-scale ...
Sep 14, 2016
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A strain of inbred mice commonly used for the creation of so-called knockout animals has been found to carry a previously undetected mutation that could affect the results of immune system research studies. In paper receiving ...
May 19, 2016
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Scientists at Columbia University's Mortimer B. Zuckerman Mind Brain Behavior Institute have developed a new viral tool that dramatically expands scientists' ability to probe the activity and circuitry of brain cells, or ...
Jan 21, 2016
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A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to ...
Feb 8, 2013
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Certain saturated fats that are common in the modern Western diet can initiate a chain of events leading to complex immune disorders such as inflammatory bowel diseases (IBD) in people with a genetic predisposition, according ...
Jun 13, 2012
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