News tagged with mouse
Researchers find new target for Alzheimer's drug development
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia
Dec 03, 2012 |
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Researchers make breakthrough in arthritis research
Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.
Medical research
Dec 03, 2012 |
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Uncovering a flaw in drug testing for chronic anxiety disorder
Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...
Medical research
Dec 13, 2012 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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Staphylococcus aureus: Why it just gets up your nose
A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. au ...
Diseases, Conditions, Syndromes
Dec 27, 2012 |
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Bacterial imbalance contributes to intestinal inflammation and carcinogenesis
Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, including inflammatory bowel disease and colorectal cancer; however, it is unclear if dysbiosis ...
Inflammatory disorders
Jan 02, 2013 |
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Modified antibodies trigger immune response, point to novel vaccine design strategies
In an approach with the potential to aid therapeutic vaccine development, Whitehead Institute scientists have shown that enzymatically modified antibodies can be used to generate highly targeted, potent responses from cells ...
Medical research
Jan 07, 2013 |
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Fusion gene contributes to glioblastoma progression
Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice.
Cancer
Jan 09, 2013 |
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New research refutes claim iPSCs are prone to immune response
(Medical Xpress)—Researchers in Japan have injected induced pluripotent stem cells (iPSCs) from mice back into genetically identical mice and report that doing so caused no immune reaction. This contradicts the results ...
Medical research
Jan 10, 2013 |
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Can we all just get along? Immunological memory learns tolerance
(Medical Xpress)—Immunology researchers at the University of Connecticut Health Center are learning more about memory T cells, which are cells that fight infection from a previously encountered antigen.
Immunology
Jan 15, 2013 |
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Calorie-restricted weight loss restores ghrelin sensitivity
(HealthDay)—In a mouse model, calorie-restricted weight loss reverses the high-fat diet-induced ghrelin resistance that may contribute to rebound weight gain, according to research published online Jan. ...
Health
Jan 21, 2013 |
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Scientists identify new strategy to fight deadly infection in cystic fibrosis
New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).
Medical research
Jan 23, 2013 |
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How the bacterium that plays role in spread of MRSA colonises the human nose
A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. aureus) ...
Diseases, Conditions, Syndromes
Jan 28, 2013 |
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Itching for new help for eczema: Recently identified immune cells possible therapeutic target
Researchers have identified a previously unknown critical role for a recently identified immune cell population in the progression of atopic dermatitis. The team found an accumulation of innate lymphoid cells ...
Immunology
Jan 30, 2013 |
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One of the key circuits in regulating genes involved in producing blood stem cells is deciphered
Researchers from the group on stem cells and cancer at IMIM (Hospital del Mar Medical Research Institute) have deciphered one of the gene regulation circuits which would make it possible to generate hematopoietic blood cells, ...
Genetics
Jan 31, 2013 |
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