Neuroscience

Testing new drugs with 'ALS-on-a-chip'

There is no cure for amyotrophic lateral sclerosis (ALS), a disease that gradually kills off the motor neurons that control muscles and is diagnosed in nearly 6,000 people per year in the United States.

Medical research

Researchers create skeletal muscle from stem cells

UCLA scientists have developed a new strategy to efficiently isolate, mature and transplant skeletal muscle cells created from human pluripotent stem cells, which can produce all cell types of the body. The findings are a ...

Medical research

Self-healing engineered muscle grown in the laboratory

Biomedical engineers have grown living skeletal muscle that looks a lot like the real thing. It contracts powerfully and rapidly, integrates into mice quickly, and for the first time, demonstrates the ability to heal itself ...

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Skeletal muscle

Skeletal muscle is a form of striated muscle tissue existing under control of the somatic nervous system. It is one of three major muscle types, the others being cardiac and smooth muscle. As its name suggests, skeletal muscle is linked to bone by bundles of collagen fibers known as tendons.

Skeletal muscle is made up of individual components known as muscle fibers. These fibers are long, cylindrical, multinucleated cells composed of actin and myosin myofibrils repeated as a sarcomere, the basic functional unit of the cell and responsible for skeletal muscle's striated appearance and forming the basic machinery necessary for muscle contraction. The term muscle refers to multiple bundles of muscle fibers held together by connective tissue.

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