Study discovers that stem cell senescence drives aging
Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor ...
Medical research
Apr 18, 2013 |
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Promoting muscle regeneration in a mouse model of muscular dystrophy
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in the protein dystrophin. Dystrophin functions to protect muscle cells from injury and loss of functional dystrophin results ...
Medical research
Apr 01, 2013 |
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Stem cells transplantation technique has high potential as a novel therapeutic strategy for ED
Transplantation of mesenchymal stem cells cultivated on the surface of nanofibrous meshes could be a novel therapeutic strategy against post-prostatectomy erectile dysfunction (ED), conclude the authors of a study which is ...
Medical research
Mar 15, 2013 |
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Researchers utilize genetically corrected stem cells to spark muscle regeneration
Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy ...
Medical research
Mar 05, 2013 |
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Study shows that human hearts generate new cells after birth
Researchers at Boston Children's Hospital have found, for the first time that young humans (infants, children and adolescents) are capable of generating new heart muscle cells. These findings refute the long-held belief that ...
Medical research
Jan 10, 2013 |
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Researchers describe a key mechanism in muscle regeneration
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have described a new selective target in muscle regeneration. This is the association of alpha-enolase protein and plasmin. The finding could be used to ...
Medical research
Dec 19, 2012 |
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The birth of new cardiac cells
Recent research has shown that there are new cells that develop in the heart, but how these cardiac cells are born and how frequently they are generated remains unclear. In new research from Brigham and Women's Hospital (BWH), ...
Cardiology
Dec 05, 2012 |
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'Junk DNA' drives embryonic development
An embryo is an amazing thing. From just one initial cell, an entire living, breathing body emerges, full of working cells and organs. It comes as no surprise that embryonic development is a very carefully ...
Genetics
Dec 03, 2012 |
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Putting a 'HEX' on muscle regeneration
A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in Bro ...
Medical research
Oct 01, 2012 |
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Dynamics of DNA packaging helps regulate formation of heart
A new regulator for heart formation has been discovered by studying how embryonic stem cells adjust the packaging of their DNA. This approach to finding genetic regulators, the scientists say, may have the ...
Medical research
Sep 27, 2012 |
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Researchers solve key part of old mystery in generating muscle mass
Working with mice, Johns Hopkins researchers have solved a key part of a muscle regeneration mystery plaguing scientists for years, adding strong support to the theory that muscle mass can be built without ...
Medical research
Sep 27, 2012 |
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At the right place at the right time—new insights into muscle stem cells
Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.
Medical research
Sep 17, 2012 |
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'Hulk' protein, Grb10, controls muscle growth
Scientists have moved closer toward helping people grow big, strong muscles without needing to hit the weight room. Australian researchers have found that by blocking the function of a protein called Grb10 while mice were ...
Medical research
Aug 30, 2012 |
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Reconnecting nerves to their target muscles
European researchers are working toward restoration of mobility in neuromuscular disease and trauma. Using miniature scaffolds to guide nerve regeneration, they are seeking to ensure proper functional connections ...
Medical research
Jul 31, 2012 |
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Lab-engineered muscle implants restore function in animals
New research shows that exercise is a key step in building a muscle-like implant in the lab with the potential to repair muscle damage from injury or disease. In mice, these implants successfully prompt the regeneration and ...
Medical research
Jul 16, 2012 |
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