Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some people diagnosed with one disorder have symptoms ...
May 12, 2023
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148
Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional ...
Mar 29, 2023
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222
The cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR) gene that are associated with the disease. The tail end of this gene's mutated ...
Sep 20, 2022
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Blocking the mutant protein with an antibody didn't stop the strange, abnormal bone growths in mice. But the knowledge gained could steer scientists toward more promising approaches, report researchers from UConn and Alexion ...
Jun 17, 2022
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A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and CIBERONC, have found the AKT inhibitor miransertib could be a new, effective molecular treatment ...
Jun 14, 2022
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In a novel experiment, a woman with advanced pancreatic cancer saw her tumors dramatically shrink after researchers in Oregon turbocharged her own immune cells, highlighting a possible new way to someday treat a variety of ...
Jun 2, 2022
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A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...
Dec 16, 2021
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Researchers at SAHMRI and the University of Adelaide have pinpointed a tumor support signal that works to suppress the immune system. Blocking this signal may prove pivotal in stopping bowel cancer.
Dec 8, 2021
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Researchers from the Brain Research Institute, Niigata University, Japan may have unraveled a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damage that could lead to Parkinson's ...
Jun 10, 2021
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An international team of scientists have identified key factors underpinning the development of bowel or colorectal cancer in patients with a genetic predisposition to the disease.
Jun 3, 2021
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