Research to understand why hereditary cancers develop resistance to a powerful cancer drug has identified an important new pathway key to chemoresistance in BRCA2-mutant cancers. The research, published in the current issue ...
Mar 5, 2015
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Up to 8 percent of people from India, Pakistan, Bangladesh and other South Asian countries carry a mutated gene that causes heart failure and potentially fatal heart attacks.
Jan 15, 2015
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Luring dormant HIV out of hiding and destroying its last cure-defying holdouts has become the holy grail of HIV eradication, but several recent attempts to do so have failed. Now the findings of a Johns Hopkins-led study ...
Jan 7, 2015
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Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have managed to generate a fruit fly (Drosophila melanogaster) model that reproduces human colon cancer. With two publications appearing in PLoS One ...
Oct 8, 2014
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Diet-induced changes in the gut's bacterial ecosystem can alter susceptibility to an autoinflammatory bone disease by modifying the immune response, St. Jude Children's Research Hospital scientists reported. The findings ...
Oct 2, 2014
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(Medical Xpress)—Scientists at the University of Pittsburgh School of Medicine have identified for the first time a key molecular mechanism by which the abnormal protein found in Huntington's disease can cause brain cell ...
May 19, 2014
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The discovery can help both in predicting the consequences of irradiation and understanding the fundamental patterns of morphogenesis. The work of the researchers has been published in PLoS One journal and is available ...
May 15, 2014
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In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins ...
Jan 28, 2014
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Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have generated the first known disease-specific induced pluripotent stem cell (iPSC) lines from a patient with familial transthyretin ...
Oct 31, 2013
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The cerebellum is a region of the brain critical for balance, learning of motor skills and coordination of movements. In the outer layer of the cerebellum, individual 'Purkinje' cells integrate inputs from the brain stem ...
Sep 20, 2013
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