Modern mice pose a challenge for medical research
The environment in which laboratory mice are reared can drastically alter the results of experiments and may have major implications for medical research around the world, according to new Australian data ...
Medical research
Jun 12, 2012 |
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Mice with big brains provide insight into brain regeneration and developmental disorders
Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. ...
Genetics
May 15, 2012 |
3.5 / 5 (4) |
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Researchers discover molecular basis of autistic symptoms in children with rare bone disorder
Children with multiple hereditary exostoses (MHE), an inherited genetic disease, suffer from multiple growths on their bones that cause pain and disfigurement. But beyond the physical symptoms of this condition, ...
Diseases, Conditions, Syndromes
Mar 12, 2012 |
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Blocking natural, marijuana-like chemical in the brain boosts fat burning
Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, ...
Medical research
Mar 06, 2012 |
4.8 / 5 (6) |
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Epigenetic culprit in Alzheimer's memory decline
In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.
Medical research
Feb 29, 2012 |
4.8 / 5 (4) |
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Common flame retardant linked to social, behavioral and learning deficits
Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning ...
Genetics
Feb 16, 2012 |
5 / 5 (3) |
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Bone marrow-derived cells differentiate in the brain through mechanisms of plasticity
Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions. Many ...
Medical research
Dec 19, 2011 |
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Gene found in humans, mice protects cornea transparency
A transparent cornea is essential for vision, which is why the eye has evolved to nourish the cornea without blood vessels. But for millions of people around the world, diseases of the eye or trauma spur the growth of blood ...
Genetics
Dec 12, 2011 |
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Characterizing a toxic offender
The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory ...
Neuroscience
Dec 09, 2011 |
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Is obesity a ciliopathy, triggered by malfunctioning primary cilia?
Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and other vertebrates?
Medical research
Dec 06, 2011 |
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Cleft lip corrected genetically in mouse model
Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way ...
Genetics
Nov 28, 2011 |
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Researchers rebuild the brain's circuitry
Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was ...
Neuroscience
Nov 24, 2011 |
4.6 / 5 (20) |
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Brain circuits connected with memory discovered
(Medical Xpress) -- A new study published last week in Science reveals the discovery of a brain pathway that helps us link events that happen close together and play a role in memories.
Neuroscience
Nov 07, 2011 |
4.7 / 5 (11) |
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Circadian clock may impact organ transplant success
Health care providers assess blood and tissue type as well as organ size and health to enhance transplant success. New research indicates that checklist might also need to include the circadian clock.
Medical research
Oct 04, 2011 |
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An 'unconventional' path to correcting cystic fibrosis
Researchers have identified an unconventional path that may correct the defect underlying cystic fibrosis, according to a report in the September 2nd issue of the journal Cell. This new treatment dramatically extends the li ...
Medical research
Sep 01, 2011 |
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