News tagged with mutant mice

Related topics: stem cells




Modern mice pose a challenge for medical research

The environment in which laboratory mice are reared can drastically alter the results of experiments and may have major implications for medical research around the world, according to new Australian data ...

Medical research created Jun 12, 2012 | popularity not rated yet | comments 0

Mice with big brains provide insight into brain regeneration and developmental disorders

Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. ...

Genetics created May 15, 2012 | popularity 3.5 / 5 (4) | comments 0 | with audio podcast

Researchers discover molecular basis of autistic symptoms in children with rare bone disorder

Children with multiple hereditary exostoses (MHE), an inherited genetic disease, suffer from multiple growths on their bones that cause pain and disfigurement. But beyond the physical symptoms of this condition, ...

Diseases, Conditions, Syndromes created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Blocking natural, marijuana-like chemical in the brain boosts fat burning

Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, ...

Medical research created Mar 06, 2012 | popularity 4.8 / 5 (6) | comments 9 | with audio podcast

Epigenetic culprit in Alzheimer's memory decline

In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.

Medical research created Feb 29, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Common flame retardant linked to social, behavioral and learning deficits

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning ...

Genetics created Feb 16, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Bone marrow-derived cells differentiate in the brain through mechanisms of plasticity

Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions. Many ...

Medical research created Dec 19, 2011 | popularity not rated yet | comments 0 | with audio podcast

Gene found in humans, mice protects cornea transparency

A transparent cornea is essential for vision, which is why the eye has evolved to nourish the cornea without blood vessels. But for millions of people around the world, diseases of the eye or trauma spur the growth of blood ...

Genetics created Dec 12, 2011 | popularity not rated yet | comments 0 | with audio podcast

Characterizing a toxic offender

The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory ...

Neuroscience created Dec 09, 2011 | popularity not rated yet | comments 0

Is obesity a ciliopathy, triggered by malfunctioning primary cilia?

Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and other vertebrates?

Medical research created Dec 06, 2011 | popularity not rated yet | comments 2

Cleft lip corrected genetically in mouse model

Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way ...

Genetics created Nov 28, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers rebuild the brain's circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was ...

Neuroscience created Nov 24, 2011 | popularity 4.6 / 5 (20) | comments 2 | with audio podcast

Brain circuits connected with memory discovered

(Medical Xpress) -- A new study published last week in Science reveals the discovery of a brain pathway that helps us link events that happen close together and play a role in memories.

Neuroscience created Nov 07, 2011 | popularity 4.7 / 5 (11) | comments 0 | with audio podcast report

Circadian clock may impact organ transplant success

Health care providers assess blood and tissue type as well as organ size and health to enhance transplant success. New research indicates that checklist might also need to include the circadian clock.

Medical research created Oct 04, 2011 | popularity not rated yet | comments 0 | with audio podcast

An 'unconventional' path to correcting cystic fibrosis

Researchers have identified an unconventional path that may correct the defect underlying cystic fibrosis, according to a report in the September 2nd issue of the journal Cell. This new treatment dramatically extends the li ...

Medical research created Sep 01, 2011 | popularity not rated yet | comments 0 | with audio podcast