In Parkinson's disease, the protein "alpha-synuclein" aggregates within neurons of patients and appears to propagate across interconnected areas of the brain. How this happens remains largely unknown. It has been proposed ...
Jan 5, 2016
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Scientists from the RIKEN Brain Science Institute have shown that a mouse strain with a mutation that leads to dysfunction of mitochondria—the "powerhouses" that provide energy to cells—spontaneously undergo periodic ...
Oct 20, 2015
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Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose ...
Jul 13, 2015
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An international team of scientists has discovered what amounts to a molecular reset button for our internal body clock. Their findings reveal a potential target to treat a range of disorders, from sleep disturbances to other ...
Apr 27, 2015
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Complex brain disorders, such as autism or schizophrenia, still puzzle scientists because their causes lie hidden in early events of brain development, which are still poorly understood. This is about to change thanks to ...
Apr 1, 2015
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McGill researchers have discovered, for the first time, the importance of a key epigenetic regulator in the development of the hippocampus, a part of the brain associated with learning, memory and neural stem cells. Epigenetic ...
Mar 10, 2015
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Everything is connected, especially in the brain. A protein called BAI1, involved in limiting the growth of brain tumors, is also critical for spatial learning and memory, researchers have discovered.
Mar 9, 2015
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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have produced an approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious ...
Jan 21, 2015
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Approximately 1 billion people worldwide have non-alcoholic fatty liver disease (NAFLD). Individuals with this disease have an increased risk of type 2 diabetes, obesity, and kidney disease. It is not clear how this disease ...
Oct 27, 2014
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Diet-induced changes in the gut's bacterial ecosystem can alter susceptibility to an autoinflammatory bone disease by modifying the immune response, St. Jude Children's Research Hospital scientists reported. The findings ...
Oct 2, 2014
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