News tagged with mutant mice

Related topics: stem cells




Researchers rebuild the brain's circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was ...

Neuroscience created Nov 24, 2011 | popularity 4.6 / 5 (20) | comments 2 | with audio podcast

Brain circuits connected with memory discovered

(Medical Xpress) -- A new study published last week in Science reveals the discovery of a brain pathway that helps us link events that happen close together and play a role in memories.

Neuroscience created Nov 07, 2011 | popularity 4.7 / 5 (11) | comments 0 | with audio podcast report

Blocking natural, marijuana-like chemical in the brain boosts fat burning

Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, ...

Medical research created Mar 06, 2012 | popularity 4.8 / 5 (6) | comments 9 | with audio podcast

Team finds mechanism that regulates production of energy-burning brown fat

Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...

Medical research created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study discovers that stem cell senescence drives aging

Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor ...

Medical research created Apr 18, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Epigenetic culprit in Alzheimer's memory decline

In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.

Medical research created Feb 29, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Novel storage mechanism allows command, control of memory

(Medical Xpress)—Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your ...

Neuroscience created Mar 05, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Common flame retardant linked to social, behavioral and learning deficits

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning ...

Genetics created Feb 16, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Mice with big brains provide insight into brain regeneration and developmental disorders

Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. ...

Genetics created May 15, 2012 | popularity 3.5 / 5 (4) | comments 0 | with audio podcast

Study shows underlying connection between 'good' cholesterol and collagen in heart health

(Medical Xpress)—Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries ...

Cardiology created Nov 01, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Genetic mutation linked with typical form of migraine

A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

Genetics created May 01, 2013 | popularity 4.5 / 5 (2) | comments 1 | with audio podcast

The genome guardian's dimmer switch: Regulating p53 is a matter of life or death

Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...

Genetics created Jun 30, 2011 | popularity 4 / 5 (2) | comments 1 | with audio podcast

Mouse study provides new clue to staying skinny on a high-fat diet

(Medical Xpress)—The mystery of why some people get fat eating high-fat foods while others can stay skinny on a diet of burgers and chips is closer to being solved.

Diabetes created May 01, 2013 | popularity 3 / 5 (2) | comments 1

Researchers discover molecular basis of autistic symptoms in children with rare bone disorder

Children with multiple hereditary exostoses (MHE), an inherited genetic disease, suffer from multiple growths on their bones that cause pain and disfigurement. But beyond the physical symptoms of this condition, ...

Diseases, Conditions, Syndromes created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Possible muscle disease therapeutic target found

The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known about how myostatin affects muscle growth, ...

Medical research created Aug 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast