Promising treatment for progeria within reach
Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria ...
Diseases, Conditions, Syndromes
May 16, 2013 |
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Scientists discover new target for personalized cancer therapy
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...
Cancer
May 02, 2013 |
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Mutant version of H5N1 flu virus found to be more preferential to human infection
(Medical Xpress)—An international team of bio-researchers has found that a mutant strain of the H5N1 influenza virus (created in a lab) has a 200-fold preference for binding with receptors in human cells, ...
Diseases, Conditions, Syndromes
Apr 25, 2013 |
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Phase 1 ALS trial is first to test antisense treatment of neurodegenerative disease
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis (ALS) – blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease – may ...
Neuroscience
Apr 03, 2013 |
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York scientists discover driving force behind prostate cancer
Scientists at the University of York have discovered the driving force behind the development of prostate cancer.
Cancer
Mar 27, 2013 |
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Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
Neuroscience
Mar 14, 2013 |
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Team finds mechanism that regulates production of energy-burning brown fat
Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...
Medical research
Mar 13, 2013 |
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Modified protein could become first effective treatment for vitiligo
Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune ...
Medical research
Feb 27, 2013 |
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New technique catalogs lymphoma-linked genetic variations
(Medical Xpress)—As anyone familiar with the X-Men knows, mutants can be either very good or very bad—or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set ...
Cancer
Dec 27, 2012 |
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Ponatinib acts against the most resistant types of chronic myeloid leukemia
A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine.
Cancer
Nov 28, 2012 |
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Researchers find chemical 'switches' for neurodegenerative diseases
By using a model, researchers at the University of Montreal have identified and "switched off" a chemical chain that causes neurodegenerative diseases such as Huntington's disease, amyotrophic lateral sclerosis and dementia. ...
Neuroscience
Nov 27, 2012 |
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Scientists tackle Huntington's disease by targeting mutant gene
Huntington's disease is an inherited, neurodegenerative disorder that usually appears in mid-adult life and leads to uncoordinated body movements and cognitive decline. The disease is due to multiple repetitions ...
Genetics
Nov 06, 2012 |
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Treating ovarian cancer: New pathways through genetics
A new discovery that sheds light on the genetic make up of ovarian cancer cells could explain why some women survive longer than others with this deadly disease. A multi-disciplinary team led by the Research Institute of ...
Cancer
Sep 24, 2012 |
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Toxic protein build-up in blood shines light on Huntington's disease
A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today ...
Neuroscience
Sep 17, 2012 |
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New collaboration to develop treatments for liver disease
A new collaboration based at the University of Cambridge will aim to discover and develop new medicines to treat liver disease.
Diseases, Conditions, Syndromes
Sep 07, 2012 |
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