News tagged with mutant protein

Related topics: mutations




'Very promising' treatment for Huntington disease discovered

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...

Diseases, Conditions, Syndromes created Feb 13, 2012 | popularity 5 / 5 (9) | comments 1 | with audio podcast

Team finds mechanism that regulates production of energy-burning brown fat

Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...

Medical research created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Researchers find chemical 'switches' for neurodegenerative diseases

By using a model, researchers at the University of Montreal have identified and "switched off" a chemical chain that causes neurodegenerative diseases such as Huntington's disease, amyotrophic lateral sclerosis and dementia. ...

Neuroscience created Nov 27, 2012 | popularity 3.8 / 5 (6) | comments 0 | with audio podcast

Promising treatment for progeria within reach

Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria ...

Diseases, Conditions, Syndromes created May 16, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Melatonin delays onset, reduces deaths in mouse model of Huntington's disease

Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and ...

Neuroscience created Oct 11, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Molecular delivery truck serves gene therapy cocktail

In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with ...

Medical research created Aug 15, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

York scientists discover driving force behind prostate cancer

Scientists at the University of York have discovered the driving force behind the development of prostate cancer.

Cancer created Mar 27, 2013 | popularity 5 / 5 (2) | comments 0

Mutant version of H5N1 flu virus found to be more preferential to human infection

(Medical Xpress)—An international team of bio-researchers has found that a mutant strain of the H5N1 influenza virus (created in a lab) has a 200-fold preference for binding with receptors in human cells, ...

Diseases, Conditions, Syndromes created Apr 25, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast report

The genome guardian's dimmer switch: Regulating p53 is a matter of life or death

Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...

Genetics created Jun 30, 2011 | popularity 4 / 5 (2) | comments 1 | with audio podcast

Disease progression halted in rat model of Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease) is an incurable adult neurodegenerative disorder that progresses to paralysis and death. Genetic mutations are the cause of disease in 5% of patients ...

Medical research created Dec 12, 2011 | popularity 5 / 5 (1) | comments 1

Gene linked to pancreatic cancer growth, study finds

A mutant protein found in nearly all pancreatic cancers plays a role not only in the cancer's development but in its continued growth, according to a new study from University of Michigan Comprehensive Cancer ...

Cancer created Jan 31, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New research could provide roadmap for more effective drug discovery for cystic fibrosis

A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene p ...

Medical research created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0

Mutations in JAK3 gene identified in subtype of lymphoma provide potential drug target

A substantial proportion of NK/T-cell lymphomas harbor Janus Kinase 3 gene mutations. Patients with these lymphomas might benefit from treatment with a Janus Kinase inhibitor according to a study published in Cancer Discovery, a jour ...

Cancer created Jun 15, 2012 | popularity 5 / 5 (1) | comments 0

New mouse model helps explain gene discovery in congenital heart disease

Scientists now have clues to how a gene mutation discovered in families affected with congenital heart disease leads to underdevelopment of the walls that separate the heart into four chambers. A Nationwide Children's Hospital ...

Genetics created Jun 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Enlisting the AIDS virus to fight cancer

(Medical Xpress)—Can HIV be transformed into a biotechnological tool for improving human health? According to a CNRS team at the Architecture et Réactivité de l'ARN (RNA Architecture and Reactivity) laboratory, ...

Genetics created Aug 29, 2012 | popularity 5 / 5 (1) | comments 0