Genetics

Mutation found in patients without a nose

A mutated gene in patients lacking a nose has been identified by an international team, a first step toward understanding nose development and possible therapies for another condition.

Neuroscience

Oxidative stress on the brain

Smith-Lemli-Opitz syndrome (SLOS) is a rare disease that occurs when patients inherit from both parents defects in the Dhcr7 gene, which encodes the last enzyme in the cholesterol biosynthesis pathway. A large portion of ...

Neuroscience

How whip-like cell appendages promote bodily fluid flow

Researchers at Nagoya University have identified a molecule that enables cell appendages called cilia to beat in a coordinated way to drive the flow of fluid around the brain; this prevents the accumulation of this fluid, ...

Oncology & Cancer

Block estrogen to treat lung disease

The strongest epidemiological risk factor for many forms of pulmonary arterial hypertension (PAH) is female gender. Increased estrogen makes females three times more likely to develop PAH, a chronic disease that eventually ...

Neuroscience

A molecule for proper neural wiring in the cerebellum

Researchers at Hokkaido University have found that the L-gutamate/L-aspartate transporter (GLAST) molecule plays an essential role in establishing and maintaining proper neural wiring of Purkinje cells in the cerebellum.

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