With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug ...
Mar 16, 2023
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Researchers from The University of Texas MD Anderson Cancer Center showed that inhibiting menin with revumenib, previously known as SNDX-5613, yielded encouraging responses for advanced acute leukemias with KMT2A rearrangements ...
Mar 15, 2023
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Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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Myelodysplastic syndromes (MDS) are a diverse group of bone marrow disorders in which immature stem cells do not mature to become red blood cells, white blood cells or platelets. Patients with higher-risk MDS tend to have ...
Mar 9, 2023
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A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells. The authors published their results in Molecular & Cellular Proteomics.
Mar 8, 2023
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Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer's disease in a mouse model, according to a new study publishing March 7 in the open ...
Mar 7, 2023
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Researchers at the National Institutes of Health show the benefits of screening adult patients in remission from acute myeloid leukemia (AML) for residual disease before receiving a bone marrow transplant. The findings, published ...
Mar 7, 2023
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A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
Scientists from Barts Cancer Institute at Queen Mary University of London and the Francis Crick Institute, have uncovered why patients with a rare type of blood cancer suffer from ineffective red blood cell production, and ...
Mar 1, 2023
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The latest research from SAHMRI and the University of Adelaide has discovered a potential new therapy for chronic myeloid leukemia (CML) patients who've achieved excellent results from current treatment and are hoping to ...
Mar 1, 2023
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