A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the ...
Sep 27, 2016
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Scientists at the University at Buffalo have identified the single transcription factor or "master switch" that initiates the critical myelination process in the brain. The research will be published online in Proceedings ...
Jun 30, 2014
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Around the world, hundreds of women infected with the Zika virus have given birth to children suffering from microcephaly or other brain defects, as the virus attacks key cells responsible for generating neurons and building ...
Dec 1, 2016
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The brain's key "breeder" cells, it turns out, do more than that. They secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding ...
Oct 21, 2012
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Induced pluripotent stem cells (iPSC) are a promising avenue for cell replacement therapy in neurologic diseases. For example, mouse and human iPSCs have been used to generate dopaminergic (DA) neurons that improve symptoms ...
Jan 24, 2012
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The cerebral cortex—the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness—has fascinated neuroscientists for centuries.
Jun 7, 2018
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Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other ...
Apr 22, 2016
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When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...
Mar 11, 2020
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Investigators at Cedars-Sinai are exploring a new way to treat amyotrophic lateral sclerosis (ALS) by transplanting specially engineered neural cells into the brain. Their new study shows the transplanted cells delayed disease ...
Apr 18, 2018
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The human brain is a highly organized, three-dimensional mass of cells responsible for our every move, thought and emotion. Snugly housed in the bony confines of the skull, it's also relatively inaccessible, making it difficult ...
May 26, 2015
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