Scientists identify molecular trigger for Alzheimer's disease
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...
Alzheimer's disease & dementia
May 20, 2013 |
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Green tea extract interferes with the formation of amyloid plaques in Alzheimer's disease
(Medical Xpress)—Researchers at the University of Michigan have found a new potential benefit of a molecule in green tea: preventing the misfolding of specific proteins in the brain.
Alzheimer's disease & dementia
Mar 05, 2013 |
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Scientists block toxic protein that plays key role in Lou Gehrig's disease
October 28, 2012— Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point ...
Medical research
Oct 28, 2012 |
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Developing stem cell model for Gaucher disease, neurodegenerative conditions
A new method of using adult stem cells as a model for the hereditary condition Gaucher disease could help accelerate the discovery of new, more effective therapies for this and other conditions such as Parkinson's, according ...
Neuroscience
Oct 15, 2012 |
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Scientists discover gene which causes rare disease in babies
A rare disease which often first presents in newborn babies has been traced to a novel genetic defect, scientists at Queen Mary, University of London have found.
Genetics
May 29, 2012 |
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Brain variants of protein associated with Huntington's and other neurodegenerative diseases identified
(Medical Xpress) -- A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research ...
Genetics
Jul 23, 2012 |
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Neurons made from stem cells drive brain activity after transplantation in laboratory model
(Medical Xpress)—Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are ...
Neuroscience
Nov 15, 2012 |
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Two proteins offer a 'clearer' way to treat Huntington's disease
In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critic ...
Neuroscience
Jul 11, 2012 |
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Study examines delayed, misdiagnosis of sporadic Jakob-Creutzfeldt disease
A medical record review study of 97 patients with the fatal, degenerative brain disorder sporadic Jakob-Creutzfeldt disease (sCJD) suggests that a correct diagnosis of the disease was often delayed by a variety of misdiagnoses, ...
Neuroscience
Sep 24, 2012 |
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Hunting neuron killers in Alzheimer's and traumatic brain injury
Levels of the protein appoptosin in the brain skyrocket in Alzheimer's disease and traumatic brain injury. Appoptosin is known for helping the body make heme, the molecule that carries iron in the blood. In a study published ...
Neuroscience
Nov 09, 2012 |
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Blood-based biomarkers may lead to earlier diagnosis of Parkinson's disease
Parkinson's disease (PD) is a progressive neurological condition. At present, it is usually diagnosed only when motor features are present. Hence, there is a need to develop objective and measurable biomarkers to improve ...
Parkinson's & Movement disorders
Jan 21, 2013 |
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Immune cell death safeguards against autoimmune disease
Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs. ...
Immunology
Sep 06, 2012 |
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Parkinson's disease: Parkin protects from neuronal cell death
Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.
Parkinson's & Movement disorders
Mar 01, 2013 |
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Scientists identify molecular system that could help develop potential treatments for neurodegenerative diseases
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.
Neuroscience
Feb 21, 2013 |
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Normal prion protein regulates iron metabolism
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
Alzheimer's disease & dementia
Mar 13, 2013 |
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