Two proteins may be intimately linked to the progression of Parkinson's disease, a relentless and disabling neurodegenerative disorder that affects millions of people around the world.
The basal ganglia (BG) are a group of subcortical brain nuclei that control automatic behavior in humans and other animal species. The BG has been found to show peculiar activity in people affected by a number of mental and ...
Adults who suffered any head injury during a 30-year study period had two times the rate of mortality than those who did not have any head injury, and mortality rates among those with moderate or severe head injuries were ...
Jan 23, 2023
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(Medical Xpress)—The motivation by fear, anger, and love to preserve self, kin, and others perches near the pinnacle of our existence. Triumph in the face of a seemingly insurmountable medical adversity by the creation ...
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism ...
Mar 3, 2013
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Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. In a report receiving advance online ...
Dec 18, 2011
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An international research team, co-led by scientists at Mayo Clinic's campus in Florida, have discovered three potential susceptibility genes for development of progressive supranuclear palsy (PSP), a rare neurodegenerative ...
Jun 19, 2011
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Cells, like ordinary households, produce "garbage" – debris and dysfunctional elements – that need disposal. When the mechanism for taking out this garbage fails, rare genetic diseases called lysosomal storage disorders ...
May 26, 2011
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Wearable devices can be used to measure a variety of signs and signals related to our health. A new study by researchers from Brigham and Women's Hospital suggests that such devices may also be able to help predict older ...
Nov 16, 2023
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A gene encoding a protein linked to tau production—tripartite motif protein 11 (TRIM11)—was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while ...
Jul 27, 2023
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Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons that do different functions such as controlling movements, processing sensory information, and making decisions. Cells of the brain and spinal cord are not readily regenerated en masse, so excessive damage can be devastating. Neurodegenerative diseases result from deterioration of neurons or their myelin sheath which over time will lead to dysfunction and disabilities resulting from this.
Some sources limit the term "degenerative" to conditions primarily affecting gray matter that are not associated with a obvious inciting event.
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