A treatment for ALS? Neural stem cell transplants slow progression of disease
(Medical Xpress)—Results from a meta-analysis of 11 independent amyotrophic lateral sclerosis research studies are giving hope to the ALS community by showing, for the first time, that the fatal disease ...
Neuroscience
Jan 03, 2013 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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Hunting neuron killers in Alzheimer's and traumatic brain injury
Levels of the protein appoptosin in the brain skyrocket in Alzheimer's disease and traumatic brain injury. Appoptosin is known for helping the body make heme, the molecule that carries iron in the blood. In a study published ...
Neuroscience
Nov 09, 2012 |
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Study gives clues to causes of motor neurone disease
(Medical Xpress)—Scientists at the University of Bath are one step further to understanding the role of one of the proteins that causes the neurodegenerative disorder, Amyotrophic Lateral Sclerosis (ALS), ...
Medical research
Oct 10, 2012 |
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Potential new class of drugs protects nerve cells in models of Parkinson's disease, amyotrophic lateral sclerosis
Researchers at the University of Iowa and the University of Texas Southwestern Medical Center in Dallas, have identified a new class of small molecules that block nerve cell death in animal models of Parkinson's disease and ...
Medical research
Oct 01, 2012 |
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Excitotoxicity and nerve cell death
Neural excitotoxicity can be involved in spinal cord injury, traumatic hearing loss and Alzheimer's. The Stressprotect project has gathered data on this often devastating phenomenon at biochemical, genomic ...
Medical research
Sep 25, 2012 |
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Master gene affects neurons that govern breathing at birth and in adulthood
When mice are born lacking the master gene Atoh1, none breathe well and all die in the newborn period. Why and how this occurs could provide new answers about sudden infant death syndrome (SIDS), but the solution has remained ...
Neuroscience
Sep 06, 2012 |
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Therapy combining exercise and neuroprotective agent shows promise for stroke victims
In a study published in the current issue of Restorative Neurology and Neuroscience scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) ...
Neuroscience
Aug 15, 2012 |
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New research yields insights into Parkinson's disease
Researchers at the University of Toronto Scarborough (UTSC) used an innovative technique to examine chemical interactions that are implicated in Parkinson's Disease.
Parkinson's & Movement disorders
Jun 04, 2012 |
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Scientists measure communication between stem cell-derived motor neurons and muscle cells
In an effort to identify the underlying causes of neurological disorders that impair motor functions such as walking and breathing, UCLA researchers have developed a novel system to measure the communication between stem ...
Neuroscience
May 05, 2012 |
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How human cells 'hold hands'
University of Iowa biologists have advanced the knowledge of human neurodevelopmental disorders by finding that a lack of a particular group of cell adhesion molecules in the cerebral cortex -- the outermost layer of the ...
Neuroscience
Apr 30, 2012 |
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Researchers have identified a gene with a key role in neuronal survival
Spanish researchers at the Institute of Neurosciences at Universitat Autonoma de Barcelona (INc-UAB) identified the fundamental role played by the Nurr1 gene in neuron survival associated with synaptic activity. The discovery, ...
Neuroscience
Apr 16, 2012 |
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Getting down to the heart of the (gray) matter to treat Parkinson's disease
An agent under consideration for use in PET imaging combats neuronal death to relieve Parkinsonian symptoms in animal models, according to a study published on April 2nd in the Journal of Experimental Medicine.
Parkinson's & Movement disorders
Apr 02, 2012 |
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Research provides new hope for those suffering from Crohn's disease
Researchers from the Hotchkiss Brain Institute (HBI) and the Snyder Institute for Chronic Diseases at the University of Calgary's Faculty of Medicine have discovered a pathway that may contribute to the symptoms related to ...
Inflammatory disorders
Mar 21, 2012 |
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