Gene therapy to reduce production of a brain protein successfully prevented development of Parkinson's disease in an animal study, according to researchers at the University of Pittsburgh School of Medicine. The findings, ...
Jun 15, 2015
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Brain researchers have been working for years on targeting a cellular process involved in neurodegeneration and cognitive dysfunction. A specialized molecular imaging agent does the job by binding to a transporter of the ...
Jun 8, 2015
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In studying the molecular biology of brain development, a team of researchers led by Ludwig Stockholm director Thomas Perlmann has discovered how disruption of a developmental mechanism alters the very nerve cells that are ...
Apr 28, 2015
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By studying nerve and liver cells grown from patient-derived induced pluripotent stem cells (iPSCs), Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) ...
May 15, 2014
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(Medical Xpress)—Neurobiologist from the Friedrich Miescher Institute for Biomedical Research proved that excitability protects motoneurons from degeneration in amyotropic lateral sclerosis, a rare neurodegenerative disease. ...
Oct 3, 2013
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Findings from postmortem studies of the brains of Huntington's Disease (HD) patients suggest that transcriptional dysregulation may be an early step in the pathogenesis of HD before symptoms appear. Other studies report transcriptional ...
Aug 26, 2013
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The group of genetic conditions known as spinocerebellar ataxias currently have no treatment or cure and are always fatal, in the case of affected children at an early age. Symptoms include a progressive lack of co-ordination ...
Jun 9, 2013
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(Medical Xpress)—Resolvins are molecules naturally produced by the body from omega-3 fatty acids - a process that can be jumpstarted by common aspirin. In a new study, published in The FASEB Journal, researchers at Karolinska ...
May 27, 2013
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Neurological disorders can have a devastating impact on the lives of sufferers and their families.
May 17, 2013
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(Medical Xpress)—When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the "stop" signal mechanism that cells ...
May 9, 2013
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