Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
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Next-generation treatments for Fragile X syndrome
A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Ita ...
Psychology & Psychiatry
Nov 29, 2012 |
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Researchers find fly receptor neurons able to communicate without synapse connections
(Medical Xpress)—Researchers at Yale University have found that neural receptors in a fly's antenna are able to communicate with one another despite a lack of synaptic connections. They suggest in their ...
Neuroscience
Nov 22, 2012 |
4.7 / 5 (3) |
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MicroRNA makes triple-negative breast cancer homesick
Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...
Cancer
Nov 21, 2012 |
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Serotonin mediates exercise-induced generation of new neurons
Mice that exercise in running wheels exhibit increased neurogenesis in the brain. Crucial to this process is serotonin signaling. These are the findings of a study by researchers at the Max Delbrück Center ...
Neuroscience
May 13, 2013 |
4.8 / 5 (4) |
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Brain diseases affecting more people and starting earlier than ever before
Professor Colin Pritchard's latest research published in Public Health journal has found that the sharp rise of dementia and other neurological deaths in people under 74 cannot be put down to the fact that we are living longer ...
Health
May 10, 2013 |
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Cellular environment controls formation and activity of neuronal connections
Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed ...
Neuroscience
May 06, 2013 |
4 / 5 (2) |
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ECE: Abnormal metabolites found in cured cushing's patients
(HealthDay)—Patients with Cushing's syndrome have abnormal brain metabolites suggestive of neuronal dysfunction even after they appeared to have been cured, according to a study presented at the annual ...
Diseases, Conditions, Syndromes
May 03, 2013 |
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Investigating devastating childhood diseases just got easier
Induced pluripotent stem cells (iPScs) from the skin of patients with Dravet syndrome (DS) show Dravet-like functional impairment when they are converted into neurons, finds research in BioMed Central's open ...
Medical research
May 01, 2013 |
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Dopamine regulates the motivation to act
The widespread belief that dopamine regulates pleasure could go down in history with the latest research results on the role of this neurotransmitter. Researchers have proved that it regulates motivation, causing individuals ...
Neuroscience
Apr 29, 2013 |
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Structure that edits messenger RNA transcripts defective in two different forms of motor neuron diseases
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a ...
Medical research
Apr 26, 2013 |
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Team finds melatonin delays ALS symptom onset and death in mice
Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at ...
Neuroscience
Apr 25, 2013 |
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Mild blast injury causes molecular changes in brain akin to Alzheimer, team says
A multicenter study led by scientists at the University of Pittsburgh School of Medicine shows that mild traumatic brain injury after blast exposure produces inflammation, oxidative stress and gene activation patterns akin ...
Neuroscience
Apr 24, 2013 |
4.5 / 5 (2) |
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Expert discusses how BRAIN Initiative will affect neuroscience
Mapping the human brain, with its billions of neurons, is one of science's most elusive projects. But a new federal program—the $100 million Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative ...
Neuroscience
Apr 24, 2013 |
5 / 5 (1) |
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New research examines connection between inflammatory stimulus and Parkinson's disease
Parkinson's disease (PD) is a progressive degenerative disease affecting a person's ability to coordinate and control their muscle movement. What starts out as a tremor in a finger will eventually lead to difficulty in writing ...
Parkinson's & Movement disorders
Apr 23, 2013 |
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