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Study details genes that control whether tumors adapt or die when faced with p53 activating drugs

When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumors die – the rest resist the challenge. A study published in the journal Cell Reports shows how: tumors that live even i ...

Cancer created May 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Four genes indentified that influence levels of 'bad' cholesterol

Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of "bad" cholesterol. This discovery could lead to the development of new drugs to reduce the ...

Medical research created May 15, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Scientists show how nerve wiring self-destructs

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the ...

Neuroscience created May 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Slowdown in health care spending growth could save Americans $770 billion, study finds

A slowdown in the growth of U.S. health care costs could mean that Americans could save as much as $770 billion on Medicare spending over the next decade, Harvard economists say.

Health created May 06, 2013 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Baby's life saved with groundbreaking 3-D printed device that restored his breathing

Every day, their baby stopped breathing, his collapsed bronchus blocking the crucial flow of air to his lungs. April and Bryan Gionfriddo watched helplessly, just praying that somehow the dire predictions ...

Medical research created May 22, 2013 | popularity 5 / 5 (4) | comments 0

'Type case' makes sparing use of laboratory animals

Researchers at the University of Twente's MIRA research institute have developed a system which may drastically reduce the use of laboratory animals in science. The system, which is designed to be implanted in laboratory ...

Other created May 16, 2013 | popularity 4 / 5 (1) | comments 0

Ethics experts call for more thoughtful optimization of drug development process

(Medical Xpress)—McGill University post-doctoral fellow Spencer Phillips Hey and Prof. Jonathan Kimmelman, Biomedical Ethics, Social Studies of Medicine, Faculty of Medicine argue that some clinical trials of new drugs ...

Medications created May 09, 2013 | popularity not rated yet | comments 0

Scientists identify early predictors of disease progression which could speed Huntington's disease drug trials

Scientists have identified a set of tests that could help identify whether and how Huntington's disease (HD) is progressing in groups of people who are not yet showing symptoms. The latest findings from the TRACK-HD study, ...

Neuroscience created May 08, 2013 | popularity not rated yet | comments 0

New drug targets skin cancer

A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye ...

Cancer created May 07, 2013 | popularity 5 / 5 (1) | comments 0

Experts discuss ways to embed patient voices and values in clinical research

There is worldwide concern in the biomedical research community that enrollment in clinical trials is lagging, putting clinical research and consequent benefits to society in jeopardy. Experts explore ways to embed patient ...

Other created Apr 30, 2013 | popularity not rated yet | comments 0

FDA announces new network to focus exclusively on patients

(HealthDay)—The U.S. Food and Drug Administration has announced the launch of a new interactive tool for educating patients, their advocates, and consumers about the processes involved in medication development.

Medications created Apr 29, 2013 | popularity not rated yet | comments 0

A new strategy required in the search for Alzheimer's drugs?

In the search for medication against Alzheimer's disease, scientists have focused – among other factors – on drugs that can break down Amyloid beta (A-beta). After all, it is the accumulation of A-beta that causes the ...

Alzheimer's disease & dementia created 21 hours ago | popularity not rated yet | comments 0

Major human drug trial underway for Alzheimer's

A potentially ground-breaking human drug trial is currently underway, which aims to discover whether blood pressure medication can slow or halt the progression of Alzheimer's Disease (AD). This is the latest ...

Alzheimer's disease & dementia created May 23, 2013 | popularity not rated yet | comments 0

Renaissance in new drugs for rare diseases

Once famously described as "orphan diseases, too small to be noticed, too small to be funded" in the Hollywood drama Lorenzo's Oil, rare diseases are getting unprecedented attention today among drug manufacturers, ...

Medications created May 13, 2013 | popularity not rated yet | comments 0

Researchers finds Irish Lupus patients likely to benefit from new treatment

Researchers from the Royal College of Surgeons in Ireland (RCSI) have discovered that a new treatment for the inflammatory condition, Systemic Lupus Erythmstosus (SLE) could potentially benefit Irish patients who suffer from ...

Arthritis & Rheumatism created May 07, 2013 | popularity not rated yet | comments 0