News tagged with nitric oxide

Researchers uncover biochemical events needed to maintain erection

For two decades, scientists have known the biochemical factors that trigger penile erection, but not what's needed to maintain one. Now an article by Johns Hopkins researchers, scheduled to be published this week by the Proceedings of ...

Medical research created Sep 26, 2012 | popularity 5 / 5 (6) | comments 6 | with audio podcast

Discovery of nitric oxide delivery mechanism may point to new avenue for treating high blood pressure

(Medical Xpress)—Researchers at the University of Virginia School of Medicine have shed new light on blood pressure regulation with the discovery of an unexpected mechanism by which hemoglobin controls the delivery of nitric ...

Medical research created Nov 14, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Antioxidants of growing interest to address infertility, erectile dysfunction

A growing body of evidence suggests that antioxidants may have significant value in addressing infertility issues in both women and men, including erectile dysfunction, and researchers say that large, specific clinical studies ...

Medical research created Jul 28, 2011 | popularity 4.4 / 5 (5) | comments 0 | with audio podcast

Exercise protects the heart via nitric oxide

Exercise both reduces the risk of a heart attack and protects the heart from injury if a heart attack does occur. For years, doctors have been trying to dissect how this second benefit of exercise works, with the aim of finding ...

Cardiology created May 04, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Inflammatory mediator enhances plaque formation in Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that causes progressive cognitive impairment and memory loss. Now, a new study published by Cell Press in the September 8 issue of the journal Neuron identi ...

Neuroscience created Sep 07, 2011 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

'Moonlighting' enzyme unravels arginine paradox

(Medical Xpress) -- Nearly 20 years ago, the journal Science tagged nitric oxide as the "molecule of the year." Since that time, researchers have tried to study and target this simple molecule that is involved in virtually every ...

Medical research created Nov 13, 2011 | popularity 5 / 5 (3) | comments 2 | with audio podcast

To combat deadly brain cancer, target the stem cells

Researchers have uncovered a new target that could stop the growth of glioblastoma, a deadly form of brain cancer. In the July 8th issue of the journal Cell, a Cell Press publication, a new study identifies an enzyme found ...

Cancer created Jul 07, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Newly discovered cell mechanism uses amplified nitric oxide to fight C. diff

Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that ...

Diseases, Conditions, Syndromes created Aug 21, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Store donated blood for more than three weeks? Say NO (nitric oxide)

Transfusion of donated blood more than three weeks old results in impaired blood vessel function, a new study of hospital patients shows. Blood banks now consider six weeks to be the maximum permitted storage time of blood ...

Medical research created Mar 10, 2013 | popularity 5 / 5 (2) | comments 1

Reversing smoke-induced damage and disease in the lung

By studying mice exposed to tobacco smoke for a period of months, researchers have new insight into how emphysema and chronic obstructive pulmonary disease (COPD) develops. In the October 14th issue of Cell they also report ...

Medical research created Oct 13, 2011 | popularity 4 / 5 (2) | comments 0

Scientists discover new molecular pathway involved in wound-healing and temperature sensation

Scientists from The Scripps Research Institute have identified a surprising new molecular pathway in skin cells that is involved in wound-healing and sensory communication.

Medical research created Jun 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New target found for nitric oxide's attack on salmonella bacteria

A new target for nitric oxide has been revealed in studies of how it inhibits the growth of Salmonella. This bacterium is a common cause of food-poisoning.

Medical research created Jul 23, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Heart drug may be effective for managing certain cancers: study

Researchers at Queen's University have identified a new mechanism that could potentially explain why the body's immune system sometimes fails to eliminate cancer. The new findings shed light on the possible cause of immune ...

Cancer created Dec 14, 2011 | popularity 5 / 5 (1) | comments 0

Inhalable nitric oxide shown safe as potential anti-microbial treatment

Results from a clinical study by a UBC-Vancouver Coastal Health research team have increased hope for a new, effective and inexpensive anti-microbial treatment using inhalable nitric oxide.

Diseases, Conditions, Syndromes created Jul 04, 2012 | popularity 5 / 5 (1) | comments 0

Bacteria producing nitric oxide extend life in roundworms

Nitric oxide, the versatile gas that helps increase blood flow, transmit nerve signals, and regulate immune function, appears to perform one more biological feat— prolonging the life of an organism and ...

Medical research created Feb 14, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Nitric oxide

Nitric oxide or nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals, including humans, and is an extremely important intermediate in the chemical industry. It is also an air pollutant produced by cigarette smoke, automobile engines and power plants.

NO is an important messenger molecule involved in many physiological and pathological processes within the mammalian body both beneficial and detrimental. Appropriate levels of NO production are important in protecting an organ such as the liver from ischemic damage. However sustained levels of NO production result in direct tissue toxicity and contribute to the vascular collapse associated with septic shock, whereas chronic expression of NO is associated with various carcinomas and inflammatory conditions including juvenile diabetes, multiple sclerosis, arthritis and ulcerative colitis.

Nitric oxide should not be confused with nitrous oxide (N2O), a general anaesthetic and greenhouse gas, or with nitrogen dioxide (NO2) which is another air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity.

Despite being a simple molecule, NO is a fundamental player in the fields of neuroscience, physiology, and immunology, and was proclaimed “Molecule of the Year” in 1992.

For more information about Nitric oxide, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.