Diseases, Conditions, Syndromes

Migraine: how to diagnose, manage and prevent

Migraine is a major cause of disability, affecting about 12% of people. A 2-part series published in CMAJ (Canadian Medical Association Journal) on diagnosing and managing the condition with both acute and preventive therapy ...

Medications

How does acetaminophen work?

Who hasn't taken acetaminophen? Known by brand names as Tylenol, Panadol, or just "non-aspirin pain reliever," we've used it to treat our headaches, pains, and fevers. Ubiquitous in medicine cabinets, it has been around a ...

Neuroscience

Opioids provide low evidence of pain relief for migraine

Evidence that opioids provide pain relief for migraine headaches is low or insufficient, a large Mayo Clinic meta-analysis published recently in JAMA has found. However, some newer therapies, along with established migraine ...

Medications

Which medications are most toxic to the liver?

A new study published in the British Journal of Clinical Pharmacology provides insights on how common hospitalized patients develop liver injury from taking different medications.

Medications

Findings of study comparing analgesics in acute post-trauma pain

The combination of a high-dose NSAID with paracetamol does not increase the analgesic effect compared to paracetamol alone. Researchers also found that paracetamol alone is superior to high-dose NSAID alone for posttraumatic ...

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