By the time we reach middle age, more than half of the oesophagus in healthy people has been taken over by cells carrying mutations in cancer genes, scientists have uncovered. By studying normal oesophagus tissue, scientists ...
Oct 18, 2018
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90
In a major step that could revolutionize biomedical research, scientists have discovered a way to keep normal cells as well as tumor cells taken from an individual cancer patient alive in the laboratory — which previously ...
Dec 19, 2011
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When normal cells grow, divide or do any job in the body, they do so in response to a whole slew of internal sensors that measure nutrients and energy supply, and environmental cues that inform what happens outside the cell. ...
Feb 12, 2019
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205
A new study has identified a drug that potentially could make a common type of immunotherapy for cancer even more effective. The study in laboratory mice found that the drug dasatinib, which is FDA-approved to treat certain ...
Feb 20, 2019
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423
For decades, scientists have tried to halt cancer by blocking nutrients from reaching tumor cells, in essence starving tumor cells of the fuel needed to grow and proliferate. Such attempts often have disappointed because ...
Jan 24, 2017
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495
Scientists at the UNC School of Medicine and NC State have created an injectable gel-like scaffold that can hold combination chemo-immunotherapeutic drugs and deliver them locally to tumors in a sequential manner. The results ...
Feb 21, 2018
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290
A new study that challenges the prevailing view of how bowel cancer develops in the large intestine is published today in Nature Medicine.
Dec 1, 2014
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0
Mayo Clinic researchers and collaborators have shown in mice that obesity increases the level of "zombie" or senescent cells in the brain, and that those cells, in turn, are linked to anxiety. When senolytic drugs are used ...
Jan 3, 2019
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240
Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic's Florida campus have discovered a way to potentially reprogram cancer cells ...
Aug 24, 2015
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2422
For almost a century, scientists have observed a strange behavior in cancer cells: They prefer a less-efficient pathway to produce energy. While normal cells utilize aerobic glycolysis to use glucose to produce 36 energy-storing ...
Sep 12, 2018
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