Diseases, Conditions, Syndromes

Genetic variation impacts pharmacokinetics of exemestane

(HealthDay)—The OATP1B1 c.521>C single nucleotide polymorphism (SNP) influences exemestane pharmacokinetics in healthy postmenopausal women, according to a study published online July 29 in the Journal of Clinical Pharmacy ...

Diseases, Conditions, Syndromes

A genetic variation may increase tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin—a peptide involved in inflammation, immunity, and control of iron levels—is associated with greater susceptibility to ...

Medical research

Where cigarette smoking's damage is done... down to your DNA

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage ...

Neuroscience

Method identifies epileptic patients who can benefit from surgery

Researchers affiliated with the University of Campinas (UNICAMP) in São Paulo State, Brazil, have shown that genetic information can be used to improve early prediction of the response to drugs in patients with mesial temporal ...

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