Oncology & Cancer

How obesity drives colon cancer in mice

Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, ...

Neuroscience

Feeding schedule maintains normal food intake in obese mice

A mouse study published in JNeurosci finds that restricting food availability to one half of the day resets the normal timing of the signals that regulate food intake and reduces weight gain in mice fed a high-fat diet.These ...

Oncology & Cancer

Identifying the mechanism in obesity's link to colon cancer

In a recent new finding, doctoral candidates Wiecang Wang and Jianan Zhang, with their advisor Guodong Zhang in the department of food science at the University of Massachusetts Amherst, report that they have identified a ...

Oncology & Cancer

Obesity inhibits key cancer defense mechanism

Obesity is a known risk factor for certain types of cancer, including colon, pancreatic and breast cancer. Studies have shown its role in promoting tumor growth and malignant progression. But its role in cancer initiation ...

Arthritis & Rheumatism

The bugs in your gut could make you weak in the knees

Bacteria in the gut, known as the gut microbiome, could be the culprit behind arthritis and joint pain that plagues people who are obese, according to a new study published today in JCI Insight.

Diabetes

Voluntary exercise and energy balance

Physical exercise alone generally fails to produce meaningful weight loss in obese individuals, and reduced non-exercise activity has been suggested to explain this observation.

Diabetes

Belly fat promotes diabetes under orders from liver

The fat that builds up deep in the abdomen—more than any other type of body fat—raises the risk of insulin resistance and type 2 diabetes. Researchers have known that abdominal fat becomes dangerous when it becomes inflamed ...

Overweight & Obesity

How obesity dulls the sense of taste

Previous studies have indicated that weight gain can reduce one's sensitivity to the taste of food, and that this effect can be reversed when the weight is lost again, but it's been unclear as to how this phenomenon arises. ...

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