Neuroscience

New clues to the origin and progression of multiple sclerosis

Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis (MS), shows that they might have a significant role in the development of the disease. The ...

Neuroscience

Team discovers surprise contributor to multiple sclerosis

Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the University of Virginia School of Medicine shows. The discovery suggests new ...

Neuroscience

Sleep boosts production of brain support cells

Sleep increases the reproduction of the cells that go on to form the insulating material on nerve cell projections in the brain and spinal cord known as myelin, according to an animal study published in the September 4 issue ...

Neuroscience

New drug target for remyelination in MS is identified

Remyelination, the spontaneous regeneration of the fatty insulator in the brain that keeps neurons communicating, has long been seen as crucial to the next big advance in treating multiple sclerosis (MS). However, a lack ...

Neuroscience

Multiple sclerosis: Damaged myelin not the trigger

Damaged myelin in the brain and spinal cord does not cause the autoimmune disease multiple sclerosis (MS), neuroimmunologists from the University of Zurich have now demonstrated in collaboration with researchers from Berlin, ...

Genetics

Key gene identified for improving multiple sclerosis treatment

The disease multiple sclerosis (MS) attacks the central nervous system and, with time, can give rise to muscle tremors and loss of balance. Researchers at Karolinska Institutet have now identified a gene, Gsta4, that protects ...

Medical research

Brain electrical activity spurs insulation of brain's wiring

(Medical Xpress) -- Researchers at the National Institutes of Health have discovered in mice a molecular trigger that initiates myelination, the process by which brain cell networks are reinforced with an insulating material ...

Medical research

Discovery offers new hope to repair spinal cord injuries

Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit signals in the spinal cord to ...

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Oligodendrocyte

Oligodendrocytes (from Greek, meaning cells with a few branches), or oligodendroglia (Greek, few tree glue), are a type of brain cell. They are a variety of neuroglia. Their main function is the insulation of axons (the long projection of nerve cells) in the central nervous system (the brain and spinal cord) of some vertebrates. (The same function is performed by Schwann cells in the peripheral nervous system). A single oligodendrocyte can extend its processes to 50 axons, wrapping around approximately 1 μm of myelin sheath around each axon; Schwann cells, on the other hand, can wrap around only 1 axon.

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