News tagged with oncogene
Related topics: cancer cells , breast cancer , tumor , cancer , tumor cells
Study reveals how transcription factor EVI1 contributes to cancer development and tumor invasion
Since its discovery close to 25 years ago, the EVI1 gene has emerged as a major player in many different types of cancer, including leukemia and tumors of the breast, prostate and colon, among other organs. ...
Cancer
Jun 20, 2012 |
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Protein may represent a switch to turn off B cell lymphoma
Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...
Cancer
May 07, 2012 |
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Outwitting a brainy gene
(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...
Cancer
May 01, 2012 |
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Advanced pancreatic tumors depend on continued oncogene activity
Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.
Cancer
Apr 26, 2012 |
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Leukaemia cells have a remembrance of things past
Although people generally talk about "cancer", it is clear that the disease occurs in a bewildering variety of forms. Even single groups of cancers, such as those of the white blood cells, may show widely differing properties. ...
Cancer
Apr 24, 2012 |
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Therapy exploits 'addiction' of leukemia cells
A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules. The research, published by Cell Press online ...
Cancer
Apr 16, 2012 |
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New compound discovered that rapidly kills liver cancer
Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...
Cancer
Mar 14, 2012 |
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Study: Muscle regeneration may provide ideal environment for rhabdomyosarcoma
Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise. These are the findings from a ...
Cancer
Feb 22, 2012 |
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Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Cancer
Feb 06, 2012 |
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New research confirms need for lung cancer testing
Different kinds of lung cancer behave in different ways, suggesting they are fundamentally different diseases. According to a University of Colorado Cancer Center study published in Cancer, the official journal of the Am ...
Cancer
Feb 02, 2012 |
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Study defines a new genetic subtype of lung cancer
A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ...
Cancer
Jan 31, 2012 |
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Study identifies a cause of resistance to colon cancer treatment
Doctors and researchers of Hospital del Mar and its research institute, the IMIM, have lead a study describing a new pharmacological resistance to cancer. This new mechanism is a mutation in an oncogene called EGFR (epidermal ...
Cancer
Jan 22, 2012 |
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Researchers identify potential target to delay metastatic pancreatic cancer and prolong survival
Often, and without much warning, pancreatic cancer cells slip through the endothelial cells, head into the blood and out to other parts of the body to metastasize, making it one of the deadliest and hardest to treat cancers ...
Cancer
Dec 21, 2011 |
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KS-herpesvirus induces reprogramming of lymphatic endothelial cells to invasive mesenchymal cells
Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma and two other rare lymphoproliferative malignancies, and it is the most common cancer in HIV-infected untreated individuals. Researchers at ...
Cancer
Dec 14, 2011 |
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Breaking oncogene's hold on cancer cell provides new treatment direction
Just as people's bodies and minds can become addicted to substances such as drugs, caffeine, alcohol, their cancers can become addicted to certain genes that insure their continued growth and dominance.
Cancer
Dec 08, 2011 |
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