News tagged with oncogene

Related topics: cancer cells , breast cancer , tumor , cancer , tumor cells

New study finds brain tumors can arise from neurons

(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, ...

Oct 19, 2012
popularity 5 / 5 (4) | comments 1 | with audio podcast report

New compound discovered that rapidly kills liver cancer

Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...

Mar 14, 2012
popularity 5 / 5 (20) | comments 0 | with audio podcast

Genetic master controls expose cancers' Achilles' heel

In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...

Apr 11, 2013
popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Some cancer mutations slow tumor growth

A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits ...

Feb 04, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Solving puzzle of B-cell lymphoma development

Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...

Sep 23, 2012
popularity 4.9 / 5 (7) | comments 0 | with audio podcast

Oncogene

An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.

Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.

This text uses material from Wikipedia licensed under CC BY-SA