News tagged with oncogene
Some cancer mutations slow tumor growth
A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits ...
Cancer
Feb 04, 2013 |
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New study finds brain tumors can arise from neurons
(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, ...
Cancer
Oct 19, 2012 |
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New gene variants raise risk of neuroblastoma, influence tumor progression
Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...
Genetics
Sep 04, 2012 |
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Potential treatment target identified in an animal model of pancreatic cancer
Detailed analysis of genes expressed in circulating tumor cells (CTCs) -- cells that break off from solid tumors and travel through the bloodstream -- has identified a potential treatment target in metastatic pancreatic cancer. ...
Cancer
Jul 01, 2012 |
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Breaking oncogene's hold on cancer cell provides new treatment direction
Just as people's bodies and minds can become addicted to substances such as drugs, caffeine, alcohol, their cancers can become addicted to certain genes that insure their continued growth and dominance.
Cancer
Dec 08, 2011 |
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Novel math formula predicts success of certain cancer therapies
Carefully tracking the rate of response of human lung tumors during the first weeks of treatment can predict which cancers will undergo sustained regression, suggests a new study by researchers at the Stanford University ...
Medical research
Oct 05, 2011 |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Cancer
Apr 11, 2013 |
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Shutting down DNA construction: How senescence halts growth of potential cancers
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...
Cancer
Apr 04, 2013 |
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Cancer researchers discover new type of retinoblastoma in babies
A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network (UHN), has discovered a new type of retinoblastoma, a rapidly developing eye ...
Cancer
Mar 12, 2013 |
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Bioelectric signals can be used to detect early cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
Medical research
Feb 01, 2013 |
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DNA-repairing protein may be key to preventing recurrence of some cancers
Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...
Cancer
Jan 28, 2013 |
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Understanding brain tumor growth opens door for non-surgical treatment
One in 25,000 people worldwide is affected by neurofibromatosis type 2 (NF2), a condition where the loss of a tumour suppressor called Merlin results in multiple tumours in the brain and nervous system.
Cancer
Jan 14, 2013 |
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Study uncovers mechanism used by BRCA1 to suppress tumors
A new study by Georgetown University Medical Center researchers reveals how a well-known tumor suppressor gene may be functioning to stop cancer cell growth.
Cancer
Dec 17, 2012 |
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Protein controlling glucose metabolism also a tumor suppressor
A protein known to regulate how cells process glucose also appears to be a tumor suppressor, adding to the potential that therapies directed at cellular metabolism may help suppress tumor growth. In their report in the Dec. ...
Cancer
Dec 06, 2012 |
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Oncogene
An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.
Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.
For more information about Oncogene, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
