Medications

Managing pain in the age of opioids

The data supporting the use of opioids to treat chronic, non-cancer pain is quite weak, says Michael Ashburn, director of the Penn Pain Medicine Center at the Perelman School of Medicine. As few as one in five patients may ...

Addiction

Opioid dependence found to permanently change brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, published Jan. 14, 2020 in PNAS, researchers ...

Medications

Speeding up the drug discovery process to help patients

An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses. This discovery was partly led by scientists ...

Medications

Drug overdose epidemic has been growing exponentially for decades

Death rates from drug overdoses in the U.S. have been on an exponential growth curve that began at least 15 years before the mid-1990s surge in opioid prescribing, suggesting that overdose death rates may continue along this ...

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