Medications

Novel botulinum toxin compound relieves chronic pain

A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, ...

Medications

Pain relief at a lower opioid dose

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...

Neuroscience

Given the choice, zebrafish willingly dose themselves with opioids

As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer ...

Neuroscience

Study identifies new drug target for chronic, touch-evoked pain

(Medical Xpress)—Researchers at the School of Medicine have identified a subset of nerve cells that mediates a form of chronic, touch-evoked pain called tactile allodynia, a condition that is resistant to conventional pain ...

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