News tagged with opioid receptor


Study shows why some pain drugs become less effective over time

Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...

Neuroscience created Apr 03, 2012 | popularity 4.4 / 5 (7) | comments 0 | with audio podcast

How a protein meal tells your brain you are full

Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signal ...

Medical research created Jul 05, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Evidence mounts for link between opioids and cancer growth

Opioid drugs used to relieve pain in postoperative and chronic cancer patients may stimulate the growth and spread of tumors, according to two studies and a commentary in the 2012 annual Journal Symposium issue of Anesthesiology, the ac ...

Cancer created Mar 20, 2012 | popularity 4.6 / 5 (5) | comments 1 | with audio podcast

Low-dose naltrexone (LDN): Tricking the body to heal itself

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) ...

Medical research created Sep 02, 2011 | popularity 5 / 5 (4) | comments 0

Study solves structure of 'salvia receptor', reveals how salvinorin A interacts with it

At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body. Salvin ...

Medical research created Mar 21, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Low dose naltrexone (LDN): Harnessing the body's own chemistry to treat human ovarian cancer

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that a low dose of the opioid antagonist naltrexone (LDN) has an extraordinarily potent antitumor effect on human ...

Cancer created Jul 12, 2011 | popularity 5 / 5 (2) | comments 0

A new promising approach in the therapy of pain

The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité – Universitätsmedizin Berlin and the Université Paris Descartes showed that ...

Medical research created Dec 04, 2012 | popularity 5 / 5 (2) | comments 0

Study offers clue as to why alcohol is addicting: Drinking releases brain endorphins

(Medical Xpress) -- Drinking alcohol leads to the release of endorphins in areas of the brain that produce feelings of pleasure and reward, according to a study led by researchers at the Ernest Gallo Clinic and Research Center ...

Neuroscience created Jan 11, 2012 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Researchers identify possible new targets for treating pain in women

Women and men experience pain, particularly chronic pain, very differently. The ability of some opioids to relieve pain also differs between women and men. While it has been recognized since the mid-nineties that some narcotic ...

Neuroscience created Aug 18, 2011 | popularity 5 / 5 (1) | comments 4 | with audio podcast

Asians fighting alcoholism may benefit from new study

(Medical Xpress) -- New UCLA psychology research indicates that Asians who are struggling with alcoholism may benefit especially from naltrexone, one of three medications approved by the U.S. Food and Drug ...

Psychology & Psychiatry created Sep 27, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Polymorphism in opioid gene affects breast cancer survival

(HealthDay) -- Genotype at the A118G polymorphism of the µ-opioid receptor gene is associated with breast cancer-specific mortality, according to a study published in the April issue of Anesthesiology.

Cancer created Mar 30, 2012 | popularity 5 / 5 (1) | comments 0

Research pinpoints, prevents stress-induced drug relapse in rats

All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study in the journal Neuron pinpoi ...

Neuroscience created Mar 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

A new treatment option for alcohol dependence: Reduced consumption rather than abstinence

A potential new treatment for alcoholism called nalmefene is effective and safe for reducing alcohol consumption in alcohol dependent individuals, says a new study published this week in Biological Psychiatry.

Psychology & Psychiatry created Apr 11, 2013 | popularity 5 / 5 (1) | comments 1

New research finds cause of morphine side effects

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...

Medical research created Apr 02, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Quick, simple test developed to identify patients who will not respond to the painkiller tramadol

French researchers have found a way to identify quickly the 5-10% of patients in whom the commonly used painkiller, tramadol, does not work effectively. A simple blood test can produce a result within a few hours, enabling ...

Medications created Jun 10, 2012 | popularity 4 / 5 (1) | comments 0