News tagged with opioids
In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.
Neuroscience Aug 14, 2012 | 4.9 / 5 (30) | 8 |
Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...
Neuroscience Apr 03, 2012 | 4.4 / 5 (7) | 0 |
(Medical Xpress)—In the first large-scale review of 400 research papers in the neurochemistry of music, a team led by Prof. Daniel J. Levitin of McGill University's Psychology Dept. has been able to show ...
Psychology & Psychiatry Mar 28, 2013 | 4.4 / 5 (7) | 0
Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signal ...
Medical research Jul 05, 2012 | 5 / 5 (5) | 0 |
Opioid drugs used to relieve pain in postoperative and chronic cancer patients may stimulate the growth and spread of tumors, according to two studies and a commentary in the 2012 annual Journal Symposium issue of Anesthesiology, the ac ...
Cancer Mar 20, 2012 | 4.6 / 5 (5) | 1 |
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) ...
Medical research Sep 02, 2011 | 5 / 5 (4) | 0
Researchers at the Indiana University School of Medicine have discovered a peptide that short circuits a pathway for chronic pain. Unlike current treatments this peptide does not exhibit deleterious side effects such as ...
Neuroscience Jun 05, 2011 | 3.8 / 5 (5) | 0 |
At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body. Salvin ...
Medical research Mar 21, 2012 | 5 / 5 (3) | 1 |
The rate of drug overdose from prescription opioids increased seven-fold in New York City over a 16-year period and was concentrated especially among white residents of the city, according to latest research at Columbia University's ...
Medications Feb 03, 2013 | 3 / 5 (4) | 0 |
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that a low dose of the opioid antagonist naltrexone (LDN) has an extraordinarily potent antitumor effect on human ...
Cancer Jul 12, 2011 | 5 / 5 (2) | 0
Mental distractions make pain easier to take, and those pain-relieving effects aren't just in your head, according to a report published online on May 17 in Current Biology.
Medical research May 17, 2012 | 5 / 5 (2) | 2 |
Governments around the world are leaving hundreds of millions of cancer patients to suffer needlessly because of their failure to ensure adequate access to pain-relieving drugs, an unprecedented new international survey reveals.
Cancer Sep 29, 2012 | 5 / 5 (2) | 3
The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité – Universitätsmedizin Berlin and the Université Paris Descartes showed that ...
Medical research Dec 04, 2012 | 5 / 5 (2) | 0
(Medical Xpress) -- Drinking alcohol leads to the release of endorphins in areas of the brain that produce feelings of pleasure and reward, according to a study led by researchers at the Ernest Gallo Clinic and Research Center ...
Neuroscience Jan 11, 2012 | 3.5 / 5 (2) | 0 |
Prescriptions for narcotic painkillers soared so much over the last decade that by 2010 enough were being dispensed to medicate every adult in the United States around the clock for a month.
Medications Feb 20, 2012 | 3.5 / 5 (2) | 1
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract. The receptors in these organ systems mediate both the beneficial effects and the side effects of opioids.
Opioids are among the world's oldest known drugs; the use of the opium poppy for its therapeutic benefits predates recorded history. The analgesic (painkiller) effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation, respiratory depression, constipation, and a strong sense of euphoria. Opioids can cause cough suppression, which can be both an indication for opioid administration or an unintended side effect. Opioid dependence can develop with ongoing administration, leading to a withdrawal syndrome with abrupt discontinuation. Opioids are well known for their ability to produce a feeling of euphoria, motivating some to recreationally use opioids.
Although the term opiate is often used as a synonym for opioid, the term opiate is properly limited to the natural alkaloids found in the resin of the opium poppy (Papaver somniferum). In some definitions, the semi-synthetic substances that are directly derived from the opium poppy are considered to be opiates as well, while in other classification systems these substances are simply referred to as semi-synthetic opioids.
For more information about Opioid, read the full article at
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